The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP
about
Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiensStructural and functional studies of the human phosphoribosyltransferase domain containing protein 1Ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate bindingThe structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferaseCrystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferaseCrystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferaseStructures of hypoxanthine-guanine phosphoribosyltransferase (TTHA0220) fromThermus thermophilusHB8Structure of Salmonella typhimurium OMP Synthase in a Complete Substrate ComplexFunctional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferasesThe crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme familiesCrystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loopStructural analyses reveal two distinct families of nucleoside phosphorylasesProbing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues.Structural trees for protein superfamilies.Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase.Pyrophosphate activation in hypoxanthine--guanine phosphoribosyltransferase with transition state analoguePurine phosphoribosyltransferases.Identification of the Bacillus subtilis pur operon repressor.Severe gouty arthritis and mild neurologic symptoms due to F199C, a newly identified variant of the hypoxanthine guanine phosphoribosyltransferase.Different oligomeric states are involved in the allosteric behavior of uracil phosphoribosyltransferase from Escherichia coli.Comparative complement selection in bacteria enables screening for lead compounds targeted to a purine salvage enzyme of parasitesHypoxanthine phosphoribosyltransferase from Trypanosoma cruzi as a target for structure-based inhibitor design: crystallization and inhibition studies with purine analogs.Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction siteCrystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution.Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase.Genotype-phenotype correlations in neurogenetics: Lesch-Nyhan disease as a model disorder.Expression of the Methanobacterium thermoautotrophicum hpt gene, encoding hypoxanthine (Guanine) phosphoribosyltransferase, in Escherichia coli.Roles for cationic residues at the quinolinic acid binding site of quinolinate phosphoribosyltransferase.Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine and a Five-Membered Heterocycle as Selective Inhibitors of Plasmodial 6-Oxopurine Phosphoribosyltransferases.Inactivation of Tritrichomonas foetus and Schistosoma mansoni purine phosphoribosyltransferases by arginine-specific reagents.Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.Converting the guanine phosphoribosyltransferase from Giardia lamblia to a hypoxanthine-guanine phosphoribosyltransferase.Specificities and pH profiles of adenine and hypoxanthine-guanine-xanthine phosphoribosyltransferases (nucleotide synthases) of the thermoacidophile archaeon Sulfolobus solfataricus.Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli.Lethal accumulation of guanylic nucleotides in Saccharomyces cerevisiae HPT1-deregulated mutants.Identification of novel mutations in the human HPRT gene.Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii.Catalytic residues Lys197 and Arg199 of Bacillus subtilis phosphoribosyl diphosphate synthase. Alanine-scanning mutagenesis of the flexible catalytic loop.Identifying Functionally Informative Evolutionary Sequence Profiles.
P2860
Q24293634-3559D84E-FADC-4BE0-A521-BE87581AE861Q24305589-FCF8F056-6BFB-4E4A-80F6-8D7538D4B76BQ27618313-565E6260-E255-41A6-8EBB-6E612C6D5BDFQ27637126-00D70F89-758D-4F6B-816F-0C63978F756FQ27639187-986BB44F-4D10-42E2-9BBD-42FB860852B7Q27648505-A207DC7A-F97A-4038-B901-A94310B93D99Q27663918-945CB498-7FE1-49ED-8D54-71FD81656070Q27678717-65378103-D0A6-4B02-9693-947EA7858185Q27679203-E724D6F4-DB0C-40C0-AD14-E55A26B8482EQ27732238-29E75BA6-28CF-4786-8445-932E3112A3E1Q27733464-C83158DD-232E-4DE6-929C-00869DE19C87Q28366428-EE7F6685-EB6F-49EB-A72F-449A859C5C7AQ30424912-6F5A5F64-E2AC-4181-AD00-D9B4A2AE992CQ30427554-60526180-98D0-4EFF-925A-59B1173F5AC6Q31001616-8A7E5767-6FCD-41D3-9511-70B1F4A7F14FQ33775608-55D9D519-F806-4CBE-B7FB-583D83CBD7BCQ33921552-33AD44EC-CDCE-4C61-A5E7-70AB0A12B298Q34057272-2E773065-8052-44F8-85A7-69577FDFF397Q34077708-032C4937-443D-4E59-AEDE-0AFEF103077CQ34401577-B1DCCD29-6E13-4D1E-9B9D-D431495B4CCDQ35112196-7F6BFA82-661C-45BF-8B21-4B40FC0F51AAQ35137562-85DEC9AE-F11C-4BAF-8FAD-C01616B8A3F9Q36515979-DCBBD51F-3BF0-41B9-829F-D714AAA2E52DQ36517997-7B076393-1DB0-4ECD-A4B0-287CBEED2900Q37369043-193C956A-5E7A-41FE-A7A2-F60BB005B11EQ37723405-29FAD80E-E887-41B8-B3C8-4715DE34CDDAQ39494805-0B448C52-9316-40DF-A3C2-5803B56C509AQ39601653-F4BF9833-C6B0-4F0A-A50E-245F6FEA5E25Q40154517-34439617-E7BE-4A4B-8F48-6D9421A2154AQ40900477-3E6DA49C-DF43-4E15-BED9-904686137D92Q41616471-8CA389D2-225E-4493-BC7A-B0864C4227D1Q41760010-6D195A4A-F422-434A-9A04-4BAC0F5D65F5Q42624945-3C198D64-36C7-40DF-A461-95A00E6E5DF3Q42646107-05FA2E4C-03A7-45B8-9982-27CB8139C896Q42846106-51F435E9-8F1C-4E27-B8B8-E1AE07D0247EQ43052927-FF0D61DA-5696-42A7-A516-9D947AFE52D8Q43663003-BCCEFCC4-BC71-421F-81B1-8018D6E65C98Q44894421-B482FDA8-7C59-45B7-B8C6-0EB0FBDA1ACBQ46594057-1AF71617-685C-4E93-AF49-96A961EB9F99Q47303116-EE153909-AF57-41EC-9865-08CDB10271CF
P2860
The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The crystal structure of human ...... osyltransferase with bound GMP
@ast
The crystal structure of human ...... osyltransferase with bound GMP
@en
The crystal structure of human ...... osyltransferase with bound GMP
@en-gb
The crystal structure of human ...... osyltransferase with bound GMP
@nl
type
label
The crystal structure of human ...... osyltransferase with bound GMP
@ast
The crystal structure of human ...... osyltransferase with bound GMP
@en
The crystal structure of human ...... osyltransferase with bound GMP
@en-gb
The crystal structure of human ...... osyltransferase with bound GMP
@nl
prefLabel
The crystal structure of human ...... osyltransferase with bound GMP
@ast
The crystal structure of human ...... osyltransferase with bound GMP
@en
The crystal structure of human ...... osyltransferase with bound GMP
@en-gb
The crystal structure of human ...... osyltransferase with bound GMP
@nl
P2093
P921
P3181
P1433
P1476
The crystal structure of human ...... osyltransferase with bound GMP
@en
P2093
P304
P3181
P356
10.1016/0092-8674(94)90301-8
P407
P577
1994-07-29T00:00:00Z