Amidation of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating monooxygenase
about
Monooxygenase X, a member of the copper-dependent monooxygenase family localized to the endoplasmic reticulumC12ORF39, a novel secreted protein with a typical amidation processing signalRegulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin CStructure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasisAmidation of Bioactive Peptides: The Structure of the Lyase Domain of the Amidating EnzymeDifferential Reactivity between Two Copper Sites in Peptidylglycine α-Hydroxylating MonooxygenaseCoordination of peroxide to the CuM center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational studyElaboration of copper-oxygen mediated C-H activation chemistry in consideration of future fuel and feedstock generationThe crystal structure of human dopamine β-hydroxylase at 2.9 Å resolutionEvidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunnelingKinetic and stereochemical studies on novel inactivators of C-terminal amidationUbiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenaseThiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase (PAM)Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processingCopper active sites in biologyEarly eukaryotic origins for cilia-associated bioactive peptide-amidating activity.Designing hydrolytic zinc metalloenzymesInfluence of glycosylation pattern on the molecular properties of monoclonal antibodies.Pam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic functionHaploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses.Imino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase.Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus.Dopamine beta-hydroxylase inactivation generates a protein-bound quinone derivative.A bioactive peptide amidating enzyme is required for ciliogenesisGenetic determinants of amidating enzyme activity and its relationship with metal cofactors in human serumCopper-peptide complex structure and reactivity when found in conserved His-X(aa)-His sequencesSulfur donor atom effects on copper(I)/O(2) chemistry with thioanisole containing tetradentate N(3)S ligand leading to μ-1,2-peroxo-dicopper(II) species.The copper centers of tyramine β-monooxygenase and its catalytic-site methionine variants: an X-ray absorption study.The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural roleOxygen Binding, Activation, and Reduction to Water by Copper Proteins.Copper dioxygen (bio)inorganic chemistryThe essential role of the Cu(II) state of Sco in the maturation of the Cu(A) center of cytochrome oxidase: evidence from H135Met and H135SeM variants of the Bacillus subtilis ScoRecombinant expression and in vitro characterisation of active Huwentoxin-IV.Secretion of Fc-amidated peptide fusion proteins by Chinese hamster ovary cells.Lumenal loop M672-P707 of the Menkes protein (ATP7A) transfers copper to peptidylglycine monooxygenase.Kβ Valence to Core X-ray Emission Studies of Cu(I) Binding Proteins with Mixed Methionine - Histidine Coordination. Relevance to the Reactivity of the M- and H-sites of Peptidylglycine MonooxygenaseStopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase.Role of a pro-sequence in the secretory pathway of prothyrotropin-releasing hormone.Effects of thioether substituents on the O2 reactivity of beta-diketiminate-Cu(I) complexes: probing the role of the methionine ligand in copper monooxygenases
P2860
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P2860
Amidation of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating monooxygenase
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@ast
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@en
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@nl
type
label
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@ast
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@en
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@nl
prefLabel
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@ast
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@en
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@nl
P2093
P3181
P1433
P1476
Amidation of bioactive peptide ...... ha-hydroxylating monooxygenase
@en
P2093
A S Kolhekar
B A Eipper
P304
P3181
P356
10.1126/SCIENCE.278.5341.1300
P407
P577
1997-11-01T00:00:00Z