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α-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson diseaseSIRT2 as a Therapeutic Target for Age-Related DisordersPhosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of ParkinsonismProgression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in miceDJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formationalpha-Synuclein and neuronal cell deathSulforaphane as a potential protective phytochemical against neurodegenerative diseasesIron and neurodegeneration: from cellular homeostasis to diseaseConformational equilibria in monomeric alpha-synuclein at the single-molecule levelStructures of the E46K mutant-type α-synuclein protein and impact of E46K mutation on the structures of the wild-type α-synuclein proteinGene therapy in Parkinson's disease: rationale and current statusParkinson's disease: from monogenic forms to genetic susceptibility factorsThe synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaBlood alpha-synuclein in agricultural pesticide handlers in central Washington StateParkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerizationMagnesium inhibits spontaneous and iron-induced aggregation of alpha-synucleinStimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3βPhosphorylation of microtubule-associated protein tau by AMPK-related kinasesRelationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicityAcceleration of alpha-synuclein aggregation by homologous peptidesSynphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synucleinTRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodiesDequalinium-induced protofibril formation of alpha-synucleinThe chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicityThe H50Q mutation enhances α-synuclein aggregation, secretion, and toxicityRedistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's diseaseSynaptic vesicle trafficking and Parkinson's diseaseUnconventional secretion of synuclein-γ promotes tumor cell invasionParkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer modelThe role of oxidative stress in Parkinson's diseaseParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingParkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradationUpregulation of alpha-synuclein by lipopolysaccharide and interleukin-1 in human macrophagesSynphilin-1A: an aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from alpha-synucleinopathy patientsPre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease modelsα-Synuclein as an intrinsically disordered monomer--fact or artefact?The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranesEvidence that alpha-synuclein does not inhibit phospholipase D
P2860
Q21090919-770B4A81-A9EF-4913-9044-3CE97F799605Q21129286-9C162CDB-2A37-4498-8313-12D31B485E53Q21131229-C2BACB5D-B8B6-4675-A530-EF12E2CEC423Q21142674-AB18351C-629C-4C56-B647-6BA4BDD751B8Q21146396-EF9BE233-EA18-4DB5-8E46-E8C0646BFC63Q21202835-0416339C-2022-405B-895D-6D6A02BF73F6Q21285068-F4732EAC-A67C-45B0-AD61-96E4195489BBQ21296730-1320DC8B-20AE-4CEE-85B1-46E9B904AFC5Q21563559-03D649D8-7CF4-40CC-A9D0-583297D6EFAAQ22061749-F11C7F73-0767-4E11-8CE4-8D8493E0CD9BQ22241423-F2E0D5AA-2910-4BCB-8575-AE11C79C2D9FQ22242870-153889E1-C076-4FB2-8830-F327CA32A662Q22252705-509AC757-D673-45DC-B474-D16CBE98CAE3Q23922069-418A54C2-4702-407F-9BB3-50C01F1CC316Q24290518-756BFC7E-9DDC-4BA3-A93F-824251B39FC9Q24291150-EBABF88F-E8E7-4F46-95BE-6F9EBEC29B3EQ24292317-B315D211-9B2A-4625-A83E-C755C4C4B06EQ24292861-497220F9-2B24-4A3D-894F-FD092B678F3AQ24292882-9E8FDE81-5D19-4CA5-8168-E2AB6017CB83Q24293089-ADFBE7E6-6A92-4696-839C-4C8C367CA19EQ24293132-C0516CBD-B841-4AE7-BDDD-BD070B8F8A4FQ24294532-B810C017-7937-45AE-BB76-43E8A3129EF6Q24296382-14E3BDFA-B1DB-4F49-915C-72ED2C4368D7Q24298122-9F179B1D-542E-4FB8-B166-71287F18955FQ24298721-764CDA61-0C8C-44F6-B94B-B7B09C3E0B44Q24299289-AD5F7B19-DE1A-4B02-ADE1-1359BB20CFFFQ24299645-B6DE4DCE-23A7-42EB-9A08-89745FD9B417Q24302024-48D4403E-61B4-4A50-B3B3-835CEA90D83EQ24304136-BB903A44-F65A-45CF-BCC2-3BB8C3F2CA19Q24305472-DEC6B3FE-80CC-428B-A328-030ED9938DD3Q24307946-6E25EE15-CC0B-41F0-B5DF-D9E13436DDD1Q24308897-ABF067D2-AD93-483A-8AE4-B0A4D9ED8BA7Q24311523-6A70002C-B9DC-409F-B785-9696BA60BD1BQ24312713-08314439-8477-4E3B-B164-F5108A21F1C8Q24314013-B8B8CA11-89E7-4753-9F00-346AD69DC98AQ24314275-2F00299C-1E43-4F97-9AA0-4E0152480459Q24315670-F44442A9-C25D-445A-B841-C0EC45052FA0Q24316089-3DF60B4C-380D-4C6F-97CF-D06C52FC0AE4Q24316619-58AFDD5C-1A6E-4300-822F-92530F4B5384Q24316900-2474D0DA-90EA-4546-B53E-BAC95B5C7789
P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Alpha-synuclein in Lewy bodies
@ast
Alpha-synuclein in Lewy bodies
@en
Alpha-synuclein in Lewy bodies
@nl
type
label
Alpha-synuclein in Lewy bodies
@ast
Alpha-synuclein in Lewy bodies
@en
Alpha-synuclein in Lewy bodies
@nl
altLabel
α-Synuclein in Lewy bodies
@en
prefLabel
Alpha-synuclein in Lewy bodies
@ast
Alpha-synuclein in Lewy bodies
@en
Alpha-synuclein in Lewy bodies
@nl
P2093
P3181
P356
P1433
P1476
Alpha-synuclein in Lewy bodies
@en
P2093
J Q Trojanowski
M G Spillantini
M L Schmidt
P2888
P304
P3181
P356
10.1038/42166
P407
P577
1997-08-28T00:00:00Z
P6179
1029460877