The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
about
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesRecognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationMDA-5 recognition of a murine norovirusInnate immune suppression enables frequent transfection with RNA encoding reprogramming proteinsArbidol: a broad-spectrum antiviral that inhibits acute and chronic HCV infectionPathogen recognition and activation of the innate immune response in zebrafishAntiviral response in pandemic influenza virusesHepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasionSIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathwaysHepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunityHepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunityDEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potentialCaspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVSATP-sensitive potassium channels mediate survival during infection in mammals and insectsHepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functionsPositive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modificationHerpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Immune signaling by RIG-I-like receptorsEmerging roles for the non-canonical IKKs in cancerViral apoptosis is induced by IRF-3-mediated activation of BaxA novel function of human Pumilio proteins in cytoplasmic sensing of viral infectionReconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunityZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerizationRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell linesRecognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.Peroxisomes are signaling platforms for antiviral innate immunitySINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANKInhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virusRetinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactionsThe E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradationViral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationInvolvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genesNegative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinaseRiplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infectionMDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signalingMAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseDDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling
P2860
Q21128787-8259C9CE-4FD6-454C-9938-9AAB19895D1AQ21131298-45DF77EE-6E80-4F2F-B6EF-904C61FC3A21Q21131596-F59EAE2E-ED0F-47B5-9452-BBB82EDB5A85Q21136251-A2A4385E-A062-4E87-9E3D-653853970E82Q21245138-CFBCBD4F-F0F2-4D51-83AE-4579BC0CFAFFQ21296719-B6876012-8AED-4072-B8A9-05B52F509966Q22305645-B830E813-6A9F-4875-A4E6-EDADDD4A1861Q24293039-9DB02A19-2586-46F1-82C6-DA656BB628B0Q24294536-D86660EB-239E-4F00-8408-488ABB8A7EA7Q24296473-9EE44880-EC71-4482-998E-3B5FC56D6415Q24297286-7D10211F-1E0E-4D89-9CAA-2EFD34A75006Q24298235-4AED89E5-0377-4294-AE13-1AADDB639380Q24298724-4DCDDFD1-24E0-4E9A-AF53-B0C6A058CA48Q24299636-C7053B41-1AAC-44E7-B39A-96E995444992Q24300957-A5BC371A-5045-4113-99CA-15EFF17E630CQ24301741-4176CA61-1C63-4E3B-A3C5-4A31B1DBBB45Q24304218-07241A01-9B40-40C9-A097-54D38146A866Q24304261-38EF3421-DA5B-41D9-B109-B2F29DA8173FQ24304438-D908AF78-B872-4EDF-8C74-A6D585747EFDQ24305225-C1B7BB48-1CDF-4CE9-A690-FFF3F7418557Q24305369-183C612E-1DD2-46E4-A14E-40555FAB41D9Q24306232-35032274-245D-4896-A5F2-AD43B779D011Q24307162-9DDE06FD-BD72-4421-8802-B9FD3848A12FQ24307928-15DE80A9-9828-46D1-991C-9F856B05388AQ24310014-E602ECCD-487E-4774-A4ED-D4B3AA6157B6Q24310270-D72030AD-2379-4D6E-8381-06945FC9973CQ24310415-1E276EE8-92D6-4F88-BD11-6DDFC6696C94Q24310706-DF158680-DC45-4328-8D42-46772C11F81EQ24310723-3CF6A56E-CCFF-46EB-8972-1C95E66D0C72Q24310727-9D4692E8-6F5A-4BC8-B6C0-0487036809FEQ24311228-7A797A37-0DAC-4FA6-AA2A-703C1A722CA3Q24313225-2681CD4E-A39C-4FF2-9E3F-82B8CFE0A51DQ24314976-10963D69-2947-47DA-8765-1967B9F18076Q24315019-4FD779D6-B934-4774-A8E9-80D5CFC3ADCCQ24315604-F7E11727-6258-4B37-9406-9DF87D0BD6D2Q24315702-DB1EE6EE-057F-45D7-98FB-8EEA19DF5914Q24315899-9FF58838-95FB-47D6-BC4B-C3BCBF35D750Q24316163-0EE862AC-8DE1-4102-B726-DAF83A1C71DDQ24316320-3A1F9181-5EDE-4BC2-92BE-465B7C08F144Q24317028-9AD848A3-E18E-4161-B0C3-89965563022A
P2860
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@ast
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@en
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@nl
type
label
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@ast
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@en
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@nl
prefLabel
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@ast
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@en
The RNA helicase RIG-I has an ...... ced innate antiviral responses
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The RNA helicase RIG-I has an ...... ed innate antiviral responses.
@en
P2093
Kazunari Taira
Mika Kikuchi
Noriaki Shinobu
Tadaatsu Imaizumi
Takashi Fujita
Takashi Natsukawa
P2860
P3181
P356
10.1038/NI1087
P407
P577
2004-07-01T00:00:00Z