Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery - Test2 - elhamkhani - TriplyDB

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

http://www.wikidata.org/entity/Q27861956

about

cyclic amine resistance locus protein cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative cyclic amine resistance locus protein, putative

P1343

Open-source syringe pump library.Open-source 3D-printable optics equipment.Next-generation antimicrobials: from chemical biology to first-in-class drugs Global phenotypic screening for antimalarials Drug resistance genomics of the antimalarial drug artemisinin Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles Recent advances in malaria drug discovery Using genetic methods to define the targets of compounds with antimalarial activity Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research Design and Synthesis of Inhibitors of Plasmodium falciparumN -Myristoyltransferase, A Promising Target for Antimalarial Drug Discovery Design and Synthesis of High Affinity Inhibitors of Plasmodium falciparum and Plasmodium vivax N -Myristoyltransferases Directed by Ligand Efficiency Dependent Lipophilicity (LELP)Antimalarial drug discovery - approaches and progress towards new medicines.Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Diversity-oriented synthesis yields novel multistage antimalarial inhibitors Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites Targeting Plasmodium PI(4)K to eliminate malaria Muddled mechanisms: recent progress towards antimalarial target identification Application of multi-target phytotherapeutic concept in malaria drug discovery: a systems biology approach in biomarker identification Contribution of high-content imaging technologies to the development of anti-infective drugs Killing the hypnozoite--drug discovery approaches to prevent relapse in Plasmodium vivax Artemisinin Action and Resistance in Plasmodium falciparum The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites The open access malaria box: a drug discovery catalyst for neglected diseases Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol Open-source colorimeter.Public domain databases for medicinal chemistry High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum A novel multiple-stage antimalarial agent that inhibits protein synthesis Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids.Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box.Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major Amastigotes In Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria Box Reveals Novel Compounds with Profound Activities against Theileria annulata Schizonts

P2860

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P1343

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P2860

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

http://www.wikidata.org/entity/Q27861956

description

2011 nî lūn-bûn

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2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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SCIENCE.1211936

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P1476

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery

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A Taylor Bright

http://www.w3.org/2001/XMLSchema#string

Advait Nagle

http://www.w3.org/2001/XMLSchema#string

Arnab Chatterjee

http://www.w3.org/2001/XMLSchema#string

Bin Zhou

http://www.w3.org/2001/XMLSchema#string

Case W McNamara

http://www.w3.org/2001/XMLSchema#string

David M Plouffe

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Dominique Mazier

http://www.w3.org/2001/XMLSchema#string

Jason Roland

http://www.w3.org/2001/XMLSchema#string

Jetsumon Sattabongkot

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Jianwei Che

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P2860

Clinical review: Severe malaria

Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain

Thousands of chemical starting points for antimalarial lead identification

Spiroindolones, a potent compound class for the treatment of malaria

Fast and accurate short read alignment with Burrows-Wheeler transform

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

The Sequence Alignment/Map format and SAMtools

Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum

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1372-1377

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scholarly article

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711275

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10.1126/SCIENCE.1211936

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6061

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334

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David A. Fidock

Elizabeth Winzeler

Stephan Meister

Ghislain M.C. Bonamy

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2011-11-17T00:00:00Z

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51808190

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22096101

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P921

cyclic amine resistance locus protein

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

cyclic amine resistance locus protein, putative

P932

3473092

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