Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
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cyclic amine resistance locus proteincyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putativecyclic amine resistance locus protein, putative
P1343
Open-source syringe pump library.Open-source 3D-printable optics equipment.Next-generation antimicrobials: from chemical biology to first-in-class drugsGlobal phenotypic screening for antimalarialsDrug resistance genomics of the antimalarial drug artemisininOpen Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos ArylpyrrolesRecent advances in malaria drug discoveryUsing genetic methods to define the targets of compounds with antimalarial activityImplementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical ResearchDesign and Synthesis of Inhibitors of Plasmodium falciparumN -Myristoyltransferase, A Promising Target for Antimalarial Drug DiscoveryDesign and Synthesis of High Affinity Inhibitors of Plasmodium falciparum and Plasmodium vivax N -Myristoyltransferases Directed by Ligand Efficiency Dependent Lipophilicity (LELP)Antimalarial drug discovery - approaches and progress towards new medicines.Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondDiversity-oriented synthesis yields novel multistage antimalarial inhibitorsMutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone AntimalarialsUDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genesIdentification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasitesTargeting Plasmodium PI(4)K to eliminate malariaMuddled mechanisms: recent progress towards antimalarial target identificationApplication of multi-target phytotherapeutic concept in malaria drug discovery: a systems biology approach in biomarker identificationContribution of high-content imaging technologies to the development of anti-infective drugsKilling the hypnozoite--drug discovery approaches to prevent relapse in Plasmodium vivaxArtemisinin Action and Resistance in Plasmodium falciparumThe activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasitesThe open access malaria box: a drug discovery catalyst for neglected diseasesDiscovery of Novel Liver-Stage Antimalarials through Quantum SimilarityScreening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar EchinococcosisCharacterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy ModelingRapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection ProtocolOpen-source colorimeter.Public domain databases for medicinal chemistryHigh-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent MalariaIdentification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparumA novel multiple-stage antimalarial agent that inhibits protein synthesisMutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug ResistanceIdentification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria boxRepurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids.Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box.Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major AmastigotesIn Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria Box Reveals Novel Compounds with Profound Activities against Theileria annulata Schizonts
P2860
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P1343
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P2860
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@ast
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@en
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@nl
type
label
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@ast
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@en
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@nl
prefLabel
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@ast
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@en
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
@nl
P2093
P2860
P50
P921
P3181
P356
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P1476
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
@en
P2093
A Taylor Bright
Advait Nagle
Arnab Chatterjee
Case W McNamara
David M Plouffe
Dominique Mazier
Jason Roland
Jetsumon Sattabongkot
Jianwei Che
P2860
P304
P3181
P356
10.1126/SCIENCE.1211936
P407
P577
2011-11-17T00:00:00Z