XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
about
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayBiochemical characterization of metnase's endonuclease activity and its role in NHEJ repairEukaryotic DNA ligases: structural and functional insightsStructural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joiningXLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligationDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayIncreased learning and brain long-term potentiation in aged mice lacking DNA polymerase μStructure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break RepairEnd-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joiningYeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining.IgH class switching and translocations use a robust non-classical end-joining pathwayThe mechanism of human nonhomologous DNA end joiningFlexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune systemA noncatalytic function of the ligation complex during nonhomologous end joining.Genome-wide mapping and assembly of structural variant breakpoints in the mouse genomeLimiting the persistence of a chromosome break diminishes its mutagenic potential.Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate.Sequence conversion by single strand oligonucleotide donors via non-homologous end joining in mammalian cellsSynthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions.Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesisMechanisms of double-strand break repair in somatic mammalian cells.Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors.Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair.Mechanism and regulation of class switch recombinationWerner protein cooperates with the XRCC4-DNA ligase IV complex in end-processingNonhomologous DNA end joining (NHEJ) and chromosomal translocations in humansYeast pol4 promotes tel1-regulated chromosomal translocations.Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight.XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV StimulationIonizing radiation-induced DNA injury and damage detection in patients with breast cancerUnexpected complexity at breakpoint junctions in phenotypically normal individuals and mechanisms involved in generating balanced translocations t(1;22)(p36;q13)Mechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining.A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo.DNA double strand break repair via non-homologous end-joining.Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ.Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ.Translesion DNA synthesis in the context of cancer research.
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P2860
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@ast
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@en
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps.
@nl
type
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XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@ast
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@en
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps.
@nl
altLabel
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@en
prefLabel
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@ast
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@en
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps.
@nl
P2093
P2860
P3181
P356
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P1476
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
@en
P2093
Brigette Tippin
Jiafeng Gu
Michael R Lieber
Myron F Goodman
Noriko Shimazaki
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601559
P407
P577
2007-02-21T00:00:00Z