Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
about
The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiencyDNA end-joining catalyzed by human cell-free extractsThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayStructural and mechanistic conservation in DNA ligasesIn vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complexPhosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinaseBiochemical characterization of metnase's endonuclease activity and its role in NHEJ repairA high-throughput scintillation proximity-based assay for human DNA ligase IVAmino acid residues in RAG1 responsible for the interaction with RAG2 during the V(D)J recombination processInteractome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathwayXLS (c9orf142) is a new component of mammalian DNA double-stranded break repairMitochondrial DNA ligase III function is independent of Xrcc1.Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementComponents of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing.DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activityCrystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.Synapsis of DNA ends by DNA-dependent protein kinaseKu recruits the XRCC4-ligase IV complex to DNA endsThe RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2Processing of DNA for nonhomologous end-joining by cell-free extractXrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IVCrystal structure of the Xrcc4 DNA repair protein and implications for end joiningFunctional redundancy between DNA ligases I and III in DNA replication in vertebrate cellsEukaryotic DNA ligases: structural and functional insightsUp-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksStructural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joiningA human XRCC4-XLF complex bridges DNABRCT domains: easy as one, two, threeXLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligationStructural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4Recruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domainForkhead-associated domain of yeast Xrs2, a homolog of human Nbs1, promotes nonhomologous end joining through interaction with a ligase IV partner protein, Lif1Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA endsMegabase chromatin domains involved in DNA double-strand breaks in vivoDeletion of Ku70, Ku80, or both causes early aging without substantially increased cancerModes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4Screening the yeast genome for new DNA-repair genes.Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joiningModulation of DNA damage and repair pathways by human tumour viruses
P2860
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P2860
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@ast
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en-gb
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@nl
type
label
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@ast
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en-gb
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@nl
prefLabel
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@ast
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en-gb
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Activity of DNA ligase IV stim ...... CC4 protein in mammalian cells
@en
P2093
P2860
P2888
P3181
P356
10.1038/41358
P407
P577
1997-07-31T00:00:00Z
P5875
P6179
1023520765