Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
about
Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stressCharacterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator proteinLAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasisThe 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteinsEvidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPKIdentification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational controlDomains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivoIsolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinaseA mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alphaPhysical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formationTranslational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinaseMammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeastMechanism and regulation of eukaryotic protein synthesisCytoplasmic p53 polypeptide is associated with ribosomesIdentification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKRThe histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acidsGenome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2pImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionIfkA, a presumptive eIF2 alpha kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound sizeHuman Cytomegalovirus Strategies to Maintain and Promote mRNA Translation'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)Drosophila as a model for unfolded protein response researchNutrient-sensing mechanisms across evolutionProtective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2Human cytomegalovirus infection activates and regulates the unfolded protein response.X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha bindingeIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcoholsGene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization toolDegradation of Saccharomyces cerevisiae transcription factor Gcn4 requires a C-terminal nuclear localization signal in the cyclin Pcl5.Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5.Yeast Gcn4p stabilization is initiated by the dissociation of the nuclear Pho85p/Pcl5p complex.Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.Amino acid-dependent Gcn4p stability regulation occurs exclusively in the yeast nucleus.Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast.
P2860
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P2860
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@ast
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@en
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@nl
type
label
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@ast
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@en
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@nl
altLabel
Phosphorylation of initiation ...... ional control of GCN4 in yeast
@en
prefLabel
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@ast
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@en
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@nl
P2093
P3181
P1433
P1476
Phosphorylation of initiation ...... onal control of GCN4 in yeast.
@en
P2093
P304
P3181
P356
10.1016/0092-8674(92)90193-G
P407
P50
P577
1992-02-07T00:00:00Z