Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.
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Phosphoinositide kinase signaling controls ER-PM cross-talk.Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil MigrationLoss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylationTORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae.Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stressSphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stressLtc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts.Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulumA neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeastChemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy.TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.TOR complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species.Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in Saccharomyces cerevisiaeMethylglyoxal activates the target of rapamycin complex 2-protein kinase C signaling pathway in Saccharomyces cerevisiae.Autophagy in the light of sphingolipid metabolismControl of Plasma Membrane Permeability by ABC Transporters.Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathwaysCharacterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial DysfunctionRegulation of cation balance in Saccharomyces cerevisiaeThe hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growthTORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development.Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy.Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.Eisosomes and plasma membrane organization.Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae.Sphingolipid homeostasis in the endoplasmic reticulum and beyond.Assessment of crosstalks between the Snf1 kinase complex and sphingolipid metabolism in S. cerevisiae via systems biology approaches.Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling.TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulationPlasma membrane organization promotes virulence of the human fungal pathogen Candida albicans.Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress.The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites.The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae.TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae.Analysis of cell cycle parameters during the transition from unhindered growth to ribosomal and translational stress conditions.Orm proteins integrate multiple signals to maintain sphingolipid homeostasis.A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast.
P2860
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P2860
Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@ast
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@en
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@nl
type
label
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@ast
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@en
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@nl
prefLabel
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@ast
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@en
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@nl
P2093
P2860
P3181
P356
P1476
Plasma membrane recruitment an ...... fector proteins Slm1 and Slm2.
@en
P2093
Andrew Hill
Ariadne Vlahakis
Brad J Niles
Huzefa Mogri
Ted Powers
P2860
P304
P3181
P356
10.1073/PNAS.1117563109
P407
P577
2012-01-31T00:00:00Z