The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
about
Shugoshin is a Mad1/Cdc20-like interactor of Mad2Kinetochore-microtubule interactions: steps towards bi-orientationStructure and function of the PP2A-shugoshin interactionShugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in miceThe centromere geometry essential for keeping mitosis error free is controlled by spindle forcesShugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeresChromosome cohesion: a cycle of holding together and falling apartCell division: control of the chromosomal passenger complex in time and spaceThe current view for the silencing of the spindle assembly checkpointCentromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligasesLoss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpointSgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis.Slk19 clusters kinetochores and facilitates chromosome bipolar attachment.Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores.Efficient chromosome biorientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1.Sgo1 regulates both condensin and Ipl1/Aurora B to promote chromosome biorientation.The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae.Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.Genetic instability in budding and fission yeast-sources and mechanismsPhosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshinMammalian SGO2 appears at the inner centromere domain and redistributes depending on tension across centromeres during meiosis II and mitosisRAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in femalesSGO1 maintains bovine meiotic and mitotic centromeric cohesions of sister chromatids and directly affects embryo developmentDNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore.Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshinSka3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosisKNL1/Spc105 recruits PP1 to silence the spindle assembly checkpointThe coordination of centromere replication, spindle formation, and kinetochore-microtubule interaction in budding yeast.Histone h3 exerts a key function in mitotic checkpoint control.Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation.Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation.Phenotypic switching in Candida glabrata accompanied by changes in expression of genes with deduced functions in copper detoxification and stressBub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast.Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast.Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosisA mad partner for Shugoshin in meiosis.Tethering sister centromeres to each other suggests the spindle checkpoint detects stretch within the kinetochore.
P2860
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P2860
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
description
2005 nî lūn-bûn
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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2005 թվականի հունվարին հրատարակված գիտական հոդված
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年论文
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name
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@ast
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@en
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@nl
type
label
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@ast
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@en
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@nl
prefLabel
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@ast
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@en
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@nl
P2093
P356
P1433
P1476
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
@en
P2093
Andrew W Murray
Bodo M Stern
Vahan B Indjeian
P356
10.1126/SCIENCE.1101366
P407
P577
2005-01-07T00:00:00Z