The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing.
about
IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient responseThe selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic dosesThe Ubiquitin System and Jasmonate SignalingBacterial ProteasomesThe 26S proteasome is a multifaceted target for anti-cancer therapiesThe pup-proteasome system of Mycobacterium tuberculosisMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsRegulation of the proteasome by ATP: implications for ischemic myocardial injury and donor heart preservationHemopressin and other bioactive peptides from cytosolic proteins: are these non-classical neuropeptides?Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturation.Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiaeADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast.The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae.Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome.Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions.Bacterial Proteasomes: Mechanistic and Functional InsightsMechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone RemodelingProteolytic processing and assembly of the C5 subunit into the proteasome complexProteasome assemblyThe ubiquitin-proteasome system in Alzheimer's diseasePim1 inhibition as a novel therapeutic strategy for Alzheimer's diseaseUnconventional serine proteases: variations on the catalytic Ser/His/Asp triad configurationSec61p-independent degradation of the tail-anchored ER membrane protein Ubc6pBlocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01Novel interactions between actin and the proteasome revealed by complex haploinsufficiencyIntrinsic nucleoside diphosphate kinase-like activity is a novel function of the 20 S proteasome.Identification of novel HLA-B27 ligands derived from polymorphic regions of its own or other class I molecules based on direct generation by 20 S proteasome.Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products.Biochemical analysis of the 20 S proteasome of Trypanosoma brucei.The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic studyWhy does threonine, and not serine, function as the active site nucleophile in proteasomes?Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish.Electrophoretic analysis of phosphorylation of the yeast 20S proteasome.Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.Role of the ubiquitin proteasome system in renal cell carcinoma.
P2860
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P2860
The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The active sites of the eukary ...... subunit precursor processing.
@ast
The active sites of the eukary ...... subunit precursor processing.
@en
The active sites of the eukary ...... subunit precursor processing.
@nl
type
label
The active sites of the eukary ...... subunit precursor processing.
@ast
The active sites of the eukary ...... subunit precursor processing.
@en
The active sites of the eukary ...... subunit precursor processing.
@nl
prefLabel
The active sites of the eukary ...... subunit precursor processing.
@ast
The active sites of the eukary ...... subunit precursor processing.
@en
The active sites of the eukary ...... subunit precursor processing.
@nl
P2093
P2860
P3181
P356
P1476
The active sites of the eukary ...... subunit precursor processing.
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.272.40.25200
P407
P577
1997-10-03T00:00:00Z