A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
about
claudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionclaudin-like apicomplexan microneme protein, putativeconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown functionconserved Apicomplexan protein, unknown function
P1343
TgPRELID, a Mitochondrial Protein Linked to Multidrug Resistance in the Parasite Toxoplasma gondiiA CRISPR toolbox to study virus-host interactionsGenetic impairment of parasite myosin motors uncovers the contribution of host cell membrane dynamics to Toxoplasma invasion forces.Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivoPlasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondiiA Glycosylphosphatidylinositol-Anchored Carbonic Anhydrase-Related Protein of Toxoplasma gondii Is Important for Rhoptry Biogenesis and Virulence.A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastidsMyosin-dependent cell-cell communication controls synchronicity of division in acute and chronic stages of Toxoplasma gondiiFunctional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.A CRISPR outlook for apicomplexans.CRISPR/Cas9-The ultimate weapon to battle infectious diseases?An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells.EuPathDB: the eukaryotic pathogen genomics database resource.Drugs in development for toxoplasmosis: advances, challenges, and current status.Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis.Toxoplasma gondii Requires Glycogen Phosphorylase for Balancing Amylopectin Storage and for Efficient Production of Brain Cysts.PhenoPlasm: a database of disruption phenotypes for malaria parasite genes.Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis.A permutation-based non-parametric analysis of CRISPR screen data.Targeting and alteration of tight junctions by bacteria and their virulence factors such as Clostridium perfringens enterotoxin.Cornerstones of CRISPR-Cas in drug discovery and therapy.The serine/threonine phosphatases of apicomplexan parasites.A druggable secretory protein maturase of Toxoplasma essential for invasion and egress.Gliding motility powers invasion and egress in Apicomplexa.Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens.Taming Parasites by Tailoring Them.PKA and Apicomplexan Parasite Diseases.Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.Toxoplasma gondii Clp family protein: TgClpB1 plays a crucial role in thermotolerance.Ablation of an Ovarian Tumor Family Deubiquitinase Exposes the Underlying Regulation Governing the Plasticity of Cell Cycle Progression in Toxoplasma gondii.Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the Toxoplasma Micronemes.A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii.ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites.Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice.Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.Genome editing technologies to fight infectious diseases.Crosstalk between PKA and PKG controls pH-dependent host cell egress of Toxoplasma gondii.Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects.New and emerging uses of CRISPR/Cas9 to genetically manipulate apicomplexan parasites.
P2860
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P248
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P1343
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P2860
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
description
2016 nî lūn-bûn
@nan
2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@ast
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@en
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@nl
type
label
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@ast
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@en
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@nl
prefLabel
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@ast
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@en
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@nl
P2093
P2860
P921
P3181
P1433
P1476
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes
@en
P2093
Diego Huet
Jacquin C Niles
Jeroen P J Saeij
My-Hang Huynh
Prathapan Thiru
Saima M Sidik
Sebastian Lourido
Suresh M Ganesan
Vern B Carruthers
P2860
P304
1423-1435.e12
P3181
P356
10.1016/J.CELL.2016.08.019
P407
P577
2016-09-08T00:00:00Z