P1889
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distributionNon-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish menFine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritabilityGenetic studies of body mass index yield new insights for obesity biologyCommon variants at 30 loci contribute to polygenic dyslipidemiaTwelve type 2 diabetes susceptibility loci identified through large-scale association analysisGenetic variants in novel pathways influence blood pressure and cardiovascular disease riskThe adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial functionGenome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetesVariants in MTNR1B influence fasting glucose levels.Six new loci associated with body mass index highlight a neuronal influence on body weight regulationA common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysisGenetic screening for the risk of type 2 diabetes: worthless or valuable?Analysis of protein-coding genetic variation in 60,706 humansMendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetesPrevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose toleranceGenetics of hypertrophic cardiomyopathy in eastern Finland: few founder mutations with benign or intermediary phenotypesLinkage of familial combined hyperlipidaemia to chromosome 1q21-q23New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes riskLarge-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetesResveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alphaEffect of valsartan on the incidence of diabetes and cardiovascular eventsChlorpropamide-alcohol flushing and coronary heart disease in non-insulin dependent diabeticsHexokinase II-deficient mice. Prenatal death of homozygotes without disturbances in glucose tolerance in heterozygotesPhosphorylation barriers to skeletal and cardiac muscle glucose uptakes in high-fat fed mice: studies in mice with a 50% reduction of hexokinase IIFinnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the METSIM CohortHexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS productionDirectional dominance on stature and cognition in diverse human populationsLow-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibilityCommon variants associated with plasma triglycerides and risk for coronary artery diseaseDiscovery and refinement of loci associated with lipid levels.A genome-wide association search for type 2 diabetes genes in African AmericansThe birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challengeGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architectureGenome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traitsGenetic variation in GIPR influences the glucose and insulin responses to an oral glucose challengeGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityMeta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexThe genetic architecture of type 2 diabetes
P50
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P50
description
Finnish diabetes researcher, p ...... professor (Academy of Finland)
@en
Fins universitair docent (1949-)
@nl
dokter asal Finlandia
@id
finnischer Arzt und Hochschullehrer
@de
suomalainen lääkäri ja akatemiaprofessori
@fi
name
Markku Laakso
@ast
Markku Laakso
@br
Markku Laakso
@ca
Markku Laakso
@co
Markku Laakso
@da
Markku Laakso
@de
Markku Laakso
@en
Markku Laakso
@es
Markku Laakso
@fi
Markku Laakso
@fo
type
label
Markku Laakso
@ast
Markku Laakso
@br
Markku Laakso
@ca
Markku Laakso
@co
Markku Laakso
@da
Markku Laakso
@de
Markku Laakso
@en
Markku Laakso
@es
Markku Laakso
@fi
Markku Laakso
@fo
altLabel
Laakso, M.
@en
Laakso, Markku
@en
prefLabel
Markku Laakso
@ast
Markku Laakso
@br
Markku Laakso
@ca
Markku Laakso
@co
Markku Laakso
@da
Markku Laakso
@de
Markku Laakso
@en
Markku Laakso
@es
Markku Laakso
@fi
Markku Laakso
@fo
P106
P166
P214
P244
P101
P1066
P1889
P19
P21
P213
0000 0000 2412 6645
P214
P244
P27
P31
P569
1949-03-28T00:00:00Z
P734
P735
P7859
lccn-n80028356