Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA
about
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-AExpression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitorPregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinaseThe metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidasesMutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincinComplex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachmentIdentification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasmaExpression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activityDiscovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A.Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism.Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivoPattern of secretion of pregnancy-associated plasma protein-A (PAPP-A) during pregnancies complicated by fetal aneuploidy, in vivo and in vitroThe role of PAPP-A in the IGF system: location, location, location.A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysisInsulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A.
P2860
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P2860
Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA
description
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Februar 1994 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/02/15)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/02/15)
@nl
наукова стаття, опублікована в лютому 1994
@uk
научни чланак (објављен 1994/02/15)
@sr
name
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@ast
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@en
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@nl
type
label
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@ast
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@en
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@nl
prefLabel
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@ast
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@en
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@nl
P2093
P356
P1433
P1476
Amino acid sequence of human p ...... ein-A derived from cloned cDNA
@en
P2093
L. Sottrup-Jensen
N. P. Møller
T. Kristensen
P304
P356
10.1021/BI00172A040
P407
P577
1994-02-15T00:00:00Z