Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin
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Protease regulation: the Yin and Yang of neural development and diseaseA novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgraftsOn the Relevance of the Met-turn Methionine in MetzincinsDuplication and diversification of the hypoxia-inducible IGFBP-1 gene in zebrafishA genome-wide screen identifies PAPP-AA-mediated IGFR signaling as a novel regulator of habituation learning.Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activityRole of ADAM and ADAMTS metalloproteinases in airway diseases.Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility.Mutation of the zinc-binding metalloprotease motif affects Bacteroides fragilis toxin activity but does not affect propeptide processing.A metalloproteinase of Coccidioides posadasii contributes to evasion of host detection.Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.Extracellular proteases as targets for drug developmentCorrelation of single nucleotide polymorphisms in the pregnancy-associated plasma protein-A gene with carotid plaques.The role of PAPP-A in the IGF system: location, location, location.Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-RatKey questions and answers about pregnancy-associated plasma protein-A.Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice.Constitutive expression of pregnancy-associated plasma protein-A in arterial smooth muscle reduces the vascular response to injury in vivo.Insulin-like growth factor (IGF) binding protein-4 is both a positive and negative regulator of IGF activity in vivo.Pregnancy-associated plasma protein A (PAPP-A) modulates the early developmental rate in zebrafish independently of its proteolytic activity.Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability.Evolution of peptidase diversity.Catalytic domain architecture of metzincin metalloproteases.PAPP-A: a promising therapeutic target for healthy longevity.Architecture and function of metallopeptidase catalytic domains.The activity of pregnancy-associated plasma protein A (PAPP-A) as expressed by immunohistochemistry in atherothrombotic plaques obtained by aspiration thrombectomy in patients presenting with a ST-elevation myocardial infarction: a brief communicatiSubstrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysisInducible knockdown of pregnancy-associated plasma protein-A gene expression in adult female mice extends life span.Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol esterOne level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiologyInsulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A.
P2860
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P2860
Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin
description
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im September 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/09/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/09/01)
@nl
наукова стаття, опублікована у вересні 2001
@uk
مقالة علمية (نشرت في سبتمبر 2001)
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name
Mutational analysis of the pro ...... classification as a metzincin
@ast
Mutational analysis of the pro ...... classification as a metzincin
@en
Mutational analysis of the pro ...... classification as a metzincin
@nl
type
label
Mutational analysis of the pro ...... classification as a metzincin
@ast
Mutational analysis of the pro ...... classification as a metzincin
@en
Mutational analysis of the pro ...... classification as a metzincin
@nl
prefLabel
Mutational analysis of the pro ...... classification as a metzincin
@ast
Mutational analysis of the pro ...... classification as a metzincin
@en
Mutational analysis of the pro ...... classification as a metzincin
@nl
P2093
P2860
P1433
P1476
Mutational analysis of the pro ...... classification as a metzincin
@en
P2093
H. B. Boldt
L. S. Laursen
L. Sottrup-Jensen
M. T. Overgaard
P2860
P304
P407
P577
2001-09-01T00:00:00Z