The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences
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Human MicroRNA targetsSingle-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRPAltered Neuronal and Circuit Excitability in Fragile X Syndrome.Fragile X syndromeThe pathophysiology of fragile X (and what it teaches us about synapses)The FMRP regulon: from targets to disease convergenceChannelopathies and dendritic dysfunction in fragile X syndrome.The unstable repeats--three evolving faces of neurological diseaseTherapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and BackAltered Translational Control of FMRP on Myelin Proteins in Neuropsychiatric DisordersA new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stabilityIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinMOV10 and FMRP regulate AGO2 association with microRNA recognition elementsThe G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancerFrom mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndromeFragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional levelFragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structurePositive feedback regulation of Akt-FMRP pathway protects neurons from cell deathGABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome.Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation proteinFragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons.Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxietyFMRP mediates mGluR5-dependent translation of amyloid precursor protein.Identification of FMRP-associated mRNAs using yeast three-hybrid system.Fragile X mental retardation protein regulates translation by binding directly to the ribosomeAnalysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequencesLocal translation of RhoA regulates growth cone collapse.Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascadesFragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloidThe fragile x mental retardation syndrome 20 years after the FMR1 gene discovery: an expanding universe of knowledge.A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse modelTargeted treatments for fragile X syndrome.Arginine methylation of RNA-binding proteins regulates cell function and differentiationSmall regulatory RNAs in mammals.The regulation of AβPP expression by RNA-binding proteinsFMRP RNA targets: identification and validation.Differential translation and fragile X syndrome.
P2860
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P2860
The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences
description
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Jahr 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/01/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/01/01)
@nl
наукова стаття, опублікована в січні 2003
@uk
مقالة علمية (نشرت عام 2003)
@ar
name
The fragile X mental retardati ...... aining U rich target sequences
@ast
The fragile X mental retardati ...... aining U rich target sequences
@en
The fragile X mental retardati ...... aining U rich target sequences
@nl
type
label
The fragile X mental retardati ...... aining U rich target sequences
@ast
The fragile X mental retardati ...... aining U rich target sequences
@en
The fragile X mental retardati ...... aining U rich target sequences
@nl
prefLabel
The fragile X mental retardati ...... aining U rich target sequences
@ast
The fragile X mental retardati ...... aining U rich target sequences
@en
The fragile X mental retardati ...... aining U rich target sequences
@nl
P2093
P3181
P1433
P1476
The fragile X mental retardati ...... aining U rich target sequences
@en
P2093
P304
P3181
P356
10.1016/S0306-4522(03)00406-8
P407
P577
2003-01-01T00:00:00Z