A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model
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Advances in the Understanding of the Gabaergic Neurobiology of FMR1 Expanded Alleles Leading to Targeted Treatments for Fragile X Spectrum DisorderTracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA GranulesThe GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome.Analyzing LC/MS metabolic profiling data in the context of existing metabolic networks.Brain region mapping using global metabolomics.Metabolic Profiling and Phenotyping of Central Nervous System Diseases: Metabolites Bring Insights into Brain Dysfunctions.Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule.A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability.Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disordersVisual sensorial impairments in neurodevelopmental disorders: evidence for a retinal phenotype in Fragile X SyndromeThe Fragile X proteins Fmrp and Fxr2p cooperate to regulate glucose metabolism in mice.Metabonomics adds a new dimension to fragile X syndrome.Dendritic targeting of short and long 3' UTR BDNF mRNA is regulated by BDNF or NT-3 and distinct sets of RNA-binding proteins.Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations.Retracted: Nrf2: a novel therapeutic target in fragile X syndrome is modulated by NNZ2566.An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability.Neurodegenerative diseases: quantitative predictions of protein-RNA interactions.The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellumMetabolic phenotyping and systems biology approaches to understanding neurological disorders.Metabolomic Analysis in Brain Research: Opportunities and ChallengesAberrant basal ganglia metabolism in fragile X syndrome: a magnetic resonance spectroscopy study.Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease.Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series.FMRP regulates actin filament organization via the armadillo protein p0071.Longitudinal in vivo developmental changes of metabolites in the hippocampus of Fmr1 knockout miceCYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Metabolome 2.0: quantitative genetics and network biology of metabolic phenotypes.MicroRNA-323-3p with clinical potential in rheumatoid arthritis, Alzheimer's disease and ectopic pregnancy.Computational tools for the secondary analysis of metabolomics experiments.Modeling Fragile X syndrome in neurogenesis: An unexpected phenotype and a novel tool for future therapies.Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis.Fragile X Syndrome FMRP Co-localizes with Regulatory Targets PSD-95, GABA Receptors, CaMKIIα, and mGluR5 at Fiber Cell Membranes in the Eye Lens.MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways.The 3' UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse.Alterations in the Sp1 binding and Fmr-1 gene expression in the cortex of the brain during maturation and aging of mouse.The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function.Developmental expression of the neuroligins and neurexins in fragile X mice.Of Men and Mice: Modeling the Fragile X Syndrome.Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
P2860
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P2860
A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A metabolomic and systems biol ...... fragile X syndrome mouse model
@ast
A metabolomic and systems biol ...... fragile X syndrome mouse model
@en
type
label
A metabolomic and systems biol ...... fragile X syndrome mouse model
@ast
A metabolomic and systems biol ...... fragile X syndrome mouse model
@en
prefLabel
A metabolomic and systems biol ...... fragile X syndrome mouse model
@ast
A metabolomic and systems biol ...... fragile X syndrome mouse model
@en
P2860
P50
P356
P1433
P1476
A metabolomic and systems biol ...... fragile X syndrome mouse model
@en
P2093
Laetitia Davidovic
Vincent Navratil
P2860
P304
P356
10.1101/GR.116764.110
P577
2011-09-07T00:00:00Z