REV1 and polymerase ζ facilitate homologous recombination repair - Test2 - elhamkhani - TriplyDB

REV1 and polymerase ζ facilitate homologous recombination repair

REV1 and polymerase ζ facilitate homologous recombination repair

http://www.wikidata.org/entity/Q28118890

about

Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks Coordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast.Inflammation-induced cell proliferation potentiates DNA damage-induced mutations in vivo Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance Structural Basis of Recruitment of DNA Polymerase by Interaction between REV1 and REV7 Proteins Structural insights into the assembly of human translesion polymerase complexes NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase η The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila Error-Prone Repair of DNA Double-Strand Breaks.Reconstitution of recombination-associated DNA synthesis with human proteins.REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ Translesion polymerase genes polymorphisms and haplotypes influence survival of osteosarcoma patients.Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells.REV3L, a promising target in regulating the chemosensitivity of cervical cancer cells.Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistance Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability.DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.DNA polymerase zeta is required for proliferation of normal mammalian cells.Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck.Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses.The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells.PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities.Homologous recombination rescues ssDNA gaps generated by nucleotide excision repair and reduced translesion DNA synthesis in yeast G2 cells.DNA damage tolerance: a double-edged sword guarding the genome Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci.A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity.Mouse models of DNA polymerases.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Translesion DNA synthesis and mutagenesis in eukaryotes REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival.c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.

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REV1 and polymerase ζ facilitate homologous recombination repair

http://www.wikidata.org/entity/Q28118890

description

2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունվարին հրատարակված գիտական հոդված

@hy

artikull shkencor

@sq

artículu científicu espublizáu en 2012

@ast

im Januar 2012 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в січні 2012

@uk

مقالة علمية (نشرت عام 2012)

@ar

name

REV1 and polymerase ζ facilitate homologous recombination repair

@ast

REV1 and polymerase ζ facilitate homologous recombination repair

@en

REV1 and polymerase ζ facilitate homologous recombination repair

@nl

type

label

REV1 and polymerase ζ facilitate homologous recombination repair

@ast

REV1 and polymerase ζ facilitate homologous recombination repair

@en

REV1 and polymerase ζ facilitate homologous recombination repair

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prefLabel

REV1 and polymerase ζ facilitate homologous recombination repair

@ast

REV1 and polymerase ζ facilitate homologous recombination repair

@en

REV1 and polymerase ζ facilitate homologous recombination repair

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Nucleic Acids Research

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REV1 and polymerase ζ facilitate homologous recombination repair

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Christine E. Canman

http://www.w3.org/2001/XMLSchema#string

Colleen L. Chute

http://www.w3.org/2001/XMLSchema#string

J. Kevin Hicks

http://www.w3.org/2001/XMLSchema#string

Joon-Young Ahn

http://www.w3.org/2001/XMLSchema#string

Julia R. Brennan

http://www.w3.org/2001/XMLSchema#string

Shilpy Sharma

http://www.w3.org/2001/XMLSchema#string

Thomas W. Glover

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P2860

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

Multiple roles of vertebrate REV genes in DNA repair and recombination

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break.

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

Increased mutagenesis and unique mutation signature associated with mitotic gene conversion

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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682–691

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4198306

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10.1093/NAR/GKR769

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2

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40

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2012-01-01T00:00:00Z

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51650576

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21926160

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3258153

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