Gout-associated uric acid crystals activate the NALP3 inflammasome
about
Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophilaRecognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationCell death programs in Yersinia immunity and pathogenesisDifferential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophagesA proposed classification of the immunological diseasesDevelopments in the scientific and clinical understanding of goutA pilot study of IL-1 inhibition by anakinra in acute goutA Shope Fibroma virus PYRIN-only protein modulates the host immune responseSintered indium-tin oxide particles induce pro-inflammatory responses in vitro, in part through inflammasome activationInterleukin-1 inhibitors for acute goutInterleukin-1 inhibitors for chronic goutInterleukin-1 inhibitors for acute goutNovel role of PKR in inflammasome activation and HMGB1 releaseFunctional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell deathActivation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionPannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptorGBP5 promotes NLRP3 inflammasome assembly and immunity in mammalsEvaluation of Nod-like receptor (NLR) effector domain interactionsInflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory responseCellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activationStaphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasomePlasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunctionTRPM2 links oxidative stress to NLRP3 inflammasome activationNanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1βLiver x receptors in atherosclerosis and inflammationMany stimuli pull the necrotic trigger, an overviewThe inflammasome: in memory of Dr. Jurg TschoppReactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous diseaseRole of the inflammasome, IL-1β, and IL-18 in bacterial infectionsThe pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activationThe genetics of hyperuricaemia and goutHorror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilizationPathogen recognition and inflammatory signaling in innate immune defensesGout--current diagnosis and treatmentThe Nalp3 inflammasome is essential for the development of silicosisInflammasomes: too big to missFunction of Nod-like receptors in microbial recognition and host defenseNOD-like receptors (NLRs): bona fide intracellular microbial sensorsInnate immune activation through Nalp3 inflammasome sensing of asbestos and silica
P2860
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P2860
Gout-associated uric acid crystals activate the NALP3 inflammasome
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Gout-associated uric acid crystals activate the NALP3 inflammasome
@ast
Gout-associated uric acid crystals activate the NALP3 inflammasome
@en
Gout-associated uric acid crystals activate the NALP3 inflammasome
@nl
type
label
Gout-associated uric acid crystals activate the NALP3 inflammasome
@ast
Gout-associated uric acid crystals activate the NALP3 inflammasome
@en
Gout-associated uric acid crystals activate the NALP3 inflammasome
@nl
prefLabel
Gout-associated uric acid crystals activate the NALP3 inflammasome
@ast
Gout-associated uric acid crystals activate the NALP3 inflammasome
@en
Gout-associated uric acid crystals activate the NALP3 inflammasome
@nl
P50
P3181
P356
P1433
P1476
Gout-associated uric acid crystals activate the NALP3 inflammasome
@en
P2093
Annick Mayor
Aubry Tardivel
P2888
P304
P3181
P356
10.1038/NATURE04516
P407
P577
2006-03-09T00:00:00Z
P5875
P6179
1039236419