about
sameAs
P101
NLR family, pyrin domain containing 3DEAH-box helicase 33Caspase 4Caspase recruitment domain family member 8Gasdermin DNLR family pyrin domain containing 6NLR family pyrin domain containing 9Caspase recruitment domain family, member 8, isoform CRA_aNLR family pyrin domain containing 1Caspase 4, apoptosis-related cysteine peptidaseDEAH (Asp-Glu-Ala-His) box polypeptide 33Gasdermin DNLR family, pyrin domain containing 1ANLR family, pyrin domain containing 9BNLR family, pyrin domain containing 1BNACHT, LRR and PYD domains-containing protein 1b allele 1NLR family, pyrin domain containing 6NACHT, LRR and PYD domains-containing protein 1b allele 5NACHT, LRR and PYD domains-containing protein 1b allele 4NACHT, LRR and PYD domains-containing protein 1b allele 3NLR family, pyrin domain containing 6NLR family, pyrin domain containing 9NLR family, pyrin domain containing 3NLR family pyrin domain containing 3
P681
Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophilaNoncanonical inflammasomes: caspase-11 activation and effector mechanismsSintered indium-tin oxide particles induce pro-inflammatory responses in vitro, in part through inflammasome activationThe inflammasomeNovel role of PKR in inflammasome activation and HMGB1 releaseIFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomesThe NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasomeHMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGEIFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionDectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasomeActivation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionThe inflammasomesThe inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-betaGBP5 promotes NLRP3 inflammasome assembly and immunity in mammalsNALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorderPromyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activationAIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASCAIM2 activates the inflammasome and cell death in response to cytoplasmic DNAAn orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasomeInflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory responseCellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activationThe adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activationCentral and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cellsUnified polymerization mechanism for the assembly of ASC-dependent inflammasomes.Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasomeTRPM2 links oxidative stress to NLRP3 inflammasome activationNanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1βThe inflammasome: in memory of Dr. Jurg TschoppDICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous diseaseRole of the inflammasome, IL-1β, and IL-18 in bacterial infectionsThe pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activationCytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesionsSilica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilizationThe Nalp3 inflammasome is essential for the development of silicosisInflammasomes: too big to missInnate immune activation through Nalp3 inflammasome sensing of asbestos and silicaNeisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasomeNeutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasomeRole of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
P921
Q14905621-8BAD547D-5A02-4E25-9150-308B6A095CB7Q21105803-C65F1AFB-4E8D-4BB4-8392-BFE5C3D86AC8Q21111755-CC6AF9CD-A1A8-43F1-A4AB-1FB431E432DCQ21112952-3103383E-FDC0-492B-968C-39D04685E01EQ21119012-18CE0CC3-33A5-48ED-ACD4-1AF09CEC94C8Q21124027-9E6A0315-9513-4E35-A9D8-95E19808852CQ21124034-BE4912A6-05A3-4FAD-BDCD-5D7AB5D750F5Q21141323-B1CC8C00-F7C2-4F68-8DC8-F3C37F86EE44Q21171805-08CBA3D6-CF71-4C96-A5C5-C891E0BFD78BQ21171805-2E4ABB46-DF8A-44FC-B1C7-C6302B5EFEF6Q21494941-5250C8F0-A8F2-461A-AA89-4BB7272D7C8EQ21983213-351E12F6-BFF4-4D43-9D48-1274E2EF375FQ21984072-60F5E86F-6674-425C-9697-32D4E8CD62A8Q21985889-3B3386F8-D6B1-43DA-9457-B93EC0DAF4DCQ21985889-42E6303D-068A-434A-9566-5745AE970F30Q21986162-3C668BC7-88E6-4FED-B426-2B09EA394EB0Q21986183-20324550-2295-472A-81DC-C8A3D72C78AFQ21986183-92328989-6B46-42B9-9C72-7DB41E32A5C3Q21986187-7FEBC593-206E-4DCD-AB80-78CDC952B168Q21986187-9A4CAF3F-5603-457A-91F1-43A839AFF44CQ21986190-D82C4BC5-F808-4B6F-8BBA-1CC5736F7F0CQ21987292-0D10D441-AEBF-4BA3-A6A0-7C5592CCA6FBQ21987292-28D7A15C-6701-4E50-9801-0839C0292256Q21987295-6A4E87A7-2723-4DF8-A8D8-10390DD82199Q21987295-EB13BA3A-0BB7-4C32-B7D7-A2FD787BAE8FQ21987296-9D259E1D-2290-479A-9E62-575D2882B80BQ21987296-A71C8509-E427-4D5D-90A6-0D4E51FB96F3Q28557896-95347755-F100-4220-ADB5-8DD9FD9D88CCQ29527256-BFD01690-9E82-4321-953A-B0E23FB75353Q30020988-F5CA3C6C-CACB-4BB5-8BE4-5A44707E8055Q4044963-F86A2E67-D4F0-4361-8920-D02EC81365D0
P681
Q21131296-03121FA2-8EB5-4AFA-A7DF-B6CFC09961AEQ21131385-979F5A2A-CED1-4969-A84B-ABB967FFA1D5Q23918175-0CE94E3A-9072-4347-AC93-EFBC5122FE77Q24276127-991DE1A9-5E38-4969-9C4A-E292E0AE9DBBQ24293509-4E891806-0C68-49ED-A296-6A5BD65F6DDCQ24295265-250AE7AF-B0B7-4A50-9263-7C241C631610Q24299627-B83D8322-4F29-4413-B41C-1D602B629B41Q24299935-EA8DBC78-BB2C-443C-94F0-D3C324417C20Q24302985-DD4971EB-4E94-4372-971A-658270FFA82EQ24303046-CED2FB84-7F67-4278-8E66-EFCA6182C089Q24303900-54B17729-44DA-45D6-859F-DD91907E2DA3Q24304087-45C06060-4579-47BF-A29D-002D6E186FFCQ24305136-8E78CFF9-F374-49D9-B9FD-0E6A05A0CA9BQ24310380-E3836394-A877-4C41-BBA4-48CB0CD5311FQ24317771-0017BE7A-CA82-4B8D-9053-414B18377C8EQ24318667-FC2E7929-0226-4655-ADD7-C01CC13A5CD6Q24319706-E63D8A42-A433-492B-A2C1-3B79AEAA1070Q24319765-8429EA08-EC4B-402B-92AC-6D5EDC2F0B5BQ24319799-9755871D-E600-4668-B212-91CB1DBB0495Q24336216-BCADEA86-C9E6-4855-B477-4CEFFF71F953Q24337324-4EE3586F-2606-41B9-B105-0AEF1861B9F0Q24338420-B440BB53-40D1-4B59-8C1E-0A4873088BE9Q24338908-5D5574DB-F4DE-4914-93C4-FD7059021CAEQ24339219-F9BDB2E3-95A9-4451-85A2-C3267E8FB909Q24594277-C1496D71-C725-492C-9210-2683D5E91760Q24600251-8F982927-C3BA-4E6A-A2C4-5F9E30A1E7DCQ24603082-B06ABB57-4E16-4EDC-B208-0F07ACD48650Q24613816-02BD2EBE-ECCD-411F-AA91-50A353B1BF56Q24621930-40724813-08D6-4531-8CB5-8CB292790C75Q24624942-A0146A71-80D4-413C-A4DF-1B01C49D0867Q24627445-8B17084E-022C-4D54-A18E-D66F6F7EDB16Q24628062-D1775D12-CC49-4574-A11C-FB8DB98F392EQ24629755-A2B049F6-6A8C-450E-BD3F-30DA0BA9DEA8Q24631966-C296F6B0-61AE-4D8D-A74E-80F83BA008BEQ24645580-74E9F36E-7909-4A18-8010-356FB0F06000Q24647337-8909D7C5-AD72-4954-8C9C-AE687AABF179Q24649598-931BEAAB-EF15-4BFF-9BC0-183B4D920E11Q24655696-F0F86292-596F-4683-9957-0DC471249FE6Q24658508-7CB5429A-4B21-4C15-B787-EF8CC869321FQ24676746-0A86D707-8326-44DC-A4E6-B724A4DB57BF
P921
description
cellulaire component
@nl
cytosolic multiprotein complex that mediates the activation of Caspase 1
@en
name
Inflamasoma
@es
Inflamazóm
@cs
Inflammasom
@de
Inflammasoma
@la
Inflammasome
@fr
Inflammasome
@nl
inflamassoma
@pt
inflammasome
@en
Инфламмасома
@ru
اینفلامازوم
@fa
type
label
Inflamasoma
@es
Inflamazóm
@cs
Inflammasom
@de
Inflammasoma
@la
Inflammasome
@fr
Inflammasome
@nl
inflamassoma
@pt
inflammasome
@en
Инфламмасома
@ru
اینفلامازوم
@fa
altLabel
GO:0061702
@en
inflammasome complex
@en
prefLabel
Inflamasoma
@es
Inflamazóm
@cs
Inflammasom
@de
Inflammasoma
@la
Inflammasome
@fr
Inflammasome
@nl
inflamassoma
@pt
inflammasome
@en
Инфламмасома
@ru
اینفلامازوم
@fa
P2581
P486
P6366
P646
P6680
P6694
P2581
P2888
P2892
P3417
Inflammasome
P361
P486
P6366
2777209026
P646
/m/04lhwzx
P6680
P6694
P686
GO:0061702