Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells
about
The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylationVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteCharacterization of cis-regulatory elements conferring mercury-induced interleukin-4 gene expression in rat mast cells: a role for signal transducer and activator of transcription 6 and TATA box binding sitesShb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection.Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.Mixed-lineage kinase control of JNK and p38 MAPK pathways.Protein kinase C-theta (PKCtheta): it's all about location, location, location.The PKC gene module: molecular biosystematics to resolve its T cell functions.Regulation of IL4 gene expression by T cells and therapeutic perspectives.Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice.Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase CProtein kinase C theta cooperates with Vav1 to induce JNK activity in T-cells.Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia.Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins.T cell expressed PKCtheta demonstrates cell-type selective function.An experimental study on the regulation of expression of Th2 cytokines from T lymphocytes by protein kinase C in asthma.Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.Human T cell leukemia virus type I Tax enhances IL-4 gene expression in T cells.Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.Selective effect of mercury on Th2-type cytokine production in humans.Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.Vav-induced activation of the human IFN-γ gene promoter is mediated by upregulation of AP-1 activity
P2860
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P2860
Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@ast
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@en
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@nl
type
label
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@ast
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@en
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@nl
prefLabel
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@ast
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@en
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@nl
P2093
P1476
Vav synergizes with protein ki ...... CD28 costimulation in T cells
@en
P2093
P304
P356
10.4049/JIMMUNOL.164.7.3829
P407
P577
2000-04-01T00:00:00Z