Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 - Test2 - elhamkhani - TriplyDB

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

http://www.wikidata.org/entity/Q28139691

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Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo Silencing of chromatin assembly factor 1 in human cells leads to cell death and loss of chromatin assembly during DNA synthesis Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses DNA damage associated with mitosis and cytokinesis failure Expression and functionality of histone H2A variants in cancer Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1 Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy Probing the dynamics of doxorubicin-DNA intercalation during the initial activation of apoptosis by fluorescence lifetime imaging microscopy (FLIM)Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation Stable gene targeting in human cells using single-strand oligonucleotides with modified bases Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells.GammaH2AX and cancer DNA double-strand breaks, recombination and synapsis: the timing of meiosis differs in grasshoppers and flies.DNA damage-induced cell death is enhanced by progression through mitosis Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cells Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.Photodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells.Speckled-like pattern in the germinal center (SLIP-GC), a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.DNA topoisomerase II-dependent control of the cell cycle progression in root meristems of Allium cepa.Several nuclear events during apoptosis depend on caspase-3 activation but do not constitute a common pathway.Residual gammaH2AX foci as an indication of lethal DNA lesions.Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1.Role of apoptosis-inducing factor (AIF) in programmed nuclear death during conjugation in Tetrahymena thermophila

P2860

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P2860

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

http://www.wikidata.org/entity/Q28139691

description

2000 nî lūn-bûn

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2000 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի մարտին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

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Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

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Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

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type

label

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

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Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

@en

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

@nl

prefLabel

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

@ast

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

@en

Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

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JBC.275.13.9390

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Journal of Biological Chemistry

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Initiation of DNA fragmentatio ...... of H2AX histone at serine 139

@en

P2093

C Boon

http://www.w3.org/2001/XMLSchema#string

E P Rogakou

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W M Bonner

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W Nieves-Neira

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Y Pommier

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P2860

Molecular characterization of mitochondrial apoptosis-inducing factor

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

Crystal structure of the nucleosome core particle at 2.8 A resolution

CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

X-linked IAP is a direct inhibitor of cell-death proteases

H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals

The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

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9390-5

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3349850

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10.1074/JBC.275.13.9390

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13

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275

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2000-03-31T00:00:00Z

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279418387

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10734083

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P921

apoptotic process

phosphorylation