Met receptor tyrosine kinase: enhanced signaling through adapter proteins - Test2 - elhamkhani - TriplyDB

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

http://www.wikidata.org/entity/Q28140219

about

Ligand-regulated binding of FAP68 to the hepatocyte growth factor receptor Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1 Association of protein tyrosine phosphatases (PTPs)-1B with c-Met receptor and modulation of corneal epithelial wound healing 8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways The MET axis as a therapeutic target.Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a Understanding and Targeting MET Signaling in Solid Tumors - Are We There Yet?Diagnosis and Prognostic Significance of c-Met in Cervical Cancer: A Meta-Analysis Biomarker development in MET-targeted therapy c-Met as a Target for Personalized Therapy Targeting RTK Signaling Pathways in Cancer MET: a critical player in tumorigenesis and therapeutic target HGF/SF-met signaling in the control of branching morphogenesis and invasion Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway Viable hypomorphic signaling mutant of the Met receptor reveals a role for hepatocyte growth factor in postnatal cerebellar development Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib.Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds.Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer management c-Met must translocate to the nucleus to initiate calcium signals.p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.MiR-34a and miR-206 act as novel prognostic and therapy biomarkers in cervical cancer.Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment Peripheral vein infusion of autologous mesenchymal stem cells in Egyptian HCV-positive patients with end-stage liver disease Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase Activating mutation in MET oncogene in familial colorectal cancer.The Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in Cancer A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.Growth factor regulation of proliferation and survival of multipotential stromal cells.Ubiquitination-dependent regulation of signaling receptors in cancer.Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype The HGF receptor c-Met is overexpressed in esophageal adenocarcinoma.Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail.Dynamic expression and localization of c-MET isoforms in the developing rat pancreas.Clinical impact of c-MET expression and genetic mutational status in colorectal cancer patients after liver resection.

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P2860

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

http://www.wikidata.org/entity/Q28140219

description

2000 nî lūn-bûn

@nan

2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@ast

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@en

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@nl

type

label

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@ast

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@en

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@nl

prefLabel

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@ast

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@en

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@nl

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P1476

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

@en

P2093

G F Vande Woude

http://www.w3.org/2001/XMLSchema#string

K A Furge

http://www.w3.org/2001/XMLSchema#string

Y W Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Rho GTPases and the actin cytoskeleton

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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P304

5582-9

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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5102272

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P356

10.1038/SJ.ONC.1203859

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49

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19

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2000-11-20T00:00:00Z

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12212951

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1017661502

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11114738

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