Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
about
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionDisruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarineApoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activityNuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferaseEndoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaDisruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cγ 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivoThe EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expressionPhosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛCRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisCyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial functionPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexCyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivationThe prolyl isomerase Pin1 in breast development and cancerDeregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerThe cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell linesHistone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob miceDNA damage response-mediated degradation of Ho endonuclease via the ubiquitin system involves its nuclear export.Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1.Mechanisms controlling subcellular localization of the G(1) cyclins Cln2p and Cln3p in budding yeast.Targeting CDK4 and CDK6: From Discovery to TherapyCyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinomaCytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancerPhosphorylation-specific prolyl isomerization: is there an underlying theme?Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismSuppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cellsIkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylationAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedRole of mitogen-activated protein kinase kinase 4 in cancerCyclin D1: polymorphism, aberrant splicing and cancer riskRegulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345A phosphatase cascade by which rewarding stimuli control nucleosomal response.Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1)Inhibition of chemokine (C-C motif) receptor 7 sialylation suppresses CCL19-stimulated proliferation, invasion and anti-anoikisBiochemical and cellular evidence demonstrating AKT-1 as a binding partner for resveratrol targeting protein NQO2Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinaseThe Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformationDisruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis
P2860
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P2860
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Phosphorylation-dependent regu ...... endent cellular transformation
@ast
Phosphorylation-dependent regu ...... endent cellular transformation
@en
Phosphorylation-dependent regu ...... endent cellular transformation
@nl
type
label
Phosphorylation-dependent regu ...... endent cellular transformation
@ast
Phosphorylation-dependent regu ...... endent cellular transformation
@en
Phosphorylation-dependent regu ...... endent cellular transformation
@nl
prefLabel
Phosphorylation-dependent regu ...... endent cellular transformation
@ast
Phosphorylation-dependent regu ...... endent cellular transformation
@en
Phosphorylation-dependent regu ...... endent cellular transformation
@nl
P2093
P2860
P356
P1433
P1476
Phosphorylation-dependent regu ...... endent cellular transformation
@en
P2093
P2860
P304
P356
10.1101/GAD.854900
P407
P577
2000-12-15T00:00:00Z