Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl - Test2 - elhamkhani - TriplyDB

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

http://www.wikidata.org/entity/Q28142095

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ABL tyrosine kinases: evolution of function, regulation, and specificity Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52 Highlight: BRCA1 and BRCA2 proteins in breast cancer Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution Insights into DNA recombination from the structure of a RAD51-BRCA2 complex Human Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54 Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer Homologous Recombination and Its Role in Carcinogenesis Cross talk of tyrosine kinases with the DNA damage signaling pathways Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?Targeting ATM-deficient CLL through interference with DNA repair pathways Targeting DNA damage response in cancer therapy Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors.The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation RAD51 protein expression is increased in canine mammary carcinomas Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.Role of ABL family kinases in cancer: from leukaemia to solid tumours Enhancing survival of mouse oocytes following chemotherapy or aging by targeting Bax and Rad51 c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency The role of the DNA damage response kinase ataxia telangiectasia mutated in neuroprotection Cancer risk and the ATM gene: a continuing debate.Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation.The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting protein Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana.Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related.ATM: a mediator of multiple responses to genotoxic stress.ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints Targeting DNA repair pathways for cancer treatment: what's new?Manipulating the mammalian genome by homologous recombination Crystal structure of a Rad51 filament.ATM, a central controller of cellular responses to DNA damage.

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P2860

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

http://www.wikidata.org/entity/Q28142095

description

1999 nî lūn-bûn

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1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1999 թվականի ապրիլին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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Journal of Biological Chemistry

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Radiation-induced assembly of ...... complex requires ATM and c-Abl

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P2860

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

Regulation of Rad51 function by c-Abl in response to DNA damage

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase.

Interaction between ATM protein and c-Abl in response to DNA damage

Stimulation by Rad52 of yeast Rad51-mediated recombination

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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