Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
about
Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactionsCentrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyGlycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activityHuman homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complexA role for ATR in the DNA damage-induced phosphorylation of p53ATM-dependent phosphorylation of nibrin in response to radiation exposureDivergent hTAFII31-binding motifs hidden in activation domainsFunctional link of BRCA1 and ataxia telangiectasia gene product in DNA damage responseRegulation and localization of the Bloom syndrome protein in response to DNA damageTelomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksSMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpointATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2ARFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damagePhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageChk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restartAberrant expression of the transcription factors snail and slug alters the response to genotoxic stressThe stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathwayp53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosisInduction of SOX4 by DNA damage is critical for p53 stabilization and functionTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replicationF-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damageA role for DEAD box 1 at DNA double-strand breaksHzf Determines cell survival upon genotoxic stress by modulating p53 transactivationPPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsKu86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementUV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalizationAutophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoMDM2-HDAC1-mediated deacetylation of p53 is required for its degradationA DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulationATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1Regulation of p53 function and stability by phosphorylationPhosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damageDNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint responseRibosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionRestoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiationRereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpointATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage
P2860
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P2860
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@ast
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en-gb
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@nl
type
label
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@ast
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en-gb
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@nl
prefLabel
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@ast
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en-gb
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@nl
P2093
P921
P3181
P1433
P1476
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
@en
P2093
C E Canman
J D Siliciano
K A Cimprich
K Sakaguchi
M B Kastan
P304
P3181
P356
10.1126/SCIENCE.281.5383.1677
P407
P577
1998-09-11T00:00:00Z