The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages - Test2 - elhamkhani - TriplyDB

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

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Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen Differentiation in neuroblastoma: diffusion-limited hypoxia induces neuro-endocrine secretory protein 55 and other markers of a chromaffin phenotype The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.Systemic VHL gene functions and the VHL disease Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis Ascorbate depletion: a critical step in nickel carcinogenesis?Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast Stimuli-Responsive Gold Nanoparticles for Cancer Diagnosis and Therapy The Response of Macrophages and Neutrophils to Hypoxia in the Context of Cancer and Other Inflammatory Diseases Glucose metabolism in gastric cancer: The cutting-edge Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis Wounds that will not heal: pervasive cellular reprogramming in cancer Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells Adipose tissue immunity and cancer HypoxamiRs and cancer: from biology to targeted therapy HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.The association between the rs11549465 polymorphism in the hif-1α gene and cancer risk: a meta-analysis Hypoxia-inducible factor 1 and breast cancer metastasis Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival Orchestration of angiogenesis by immune cells Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis A unique SUMO-2-interacting motif within LANA is essential for KSHV latency Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha The biological functions of Naa10 - From amino-terminal acetylation to human disease Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104 Loss of HIF-1α in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics HIF-1alpha is essential for myeloid cell-mediated inflammation Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation HIF hydroxylation and cellular oxygen sensing.Hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients.Rationale of hyperthermia for radio(chemo)therapy and immune responses in patients with bladder cancer: Biological concepts, clinical data, interdisciplinary treatment decisions and biological tumour imaging.The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors.

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P2860

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

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2000 nî lūn-bûn

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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի օգոստոսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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The American Journal of Pathology

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Christopher W. Pugh

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Helen Turley

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

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