Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)
about
The Heterochromatin Protein 1 familyTOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinaseThe 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cellsThe 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugsPIM-1 kinase interacts with the DNA binding domain of the vitamin D receptor: a further kinase implicated in 1,25-(OH)2D3 signalingMolecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essentialPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersHP1a: a structural chromosomal protein regulating transcriptionPAP-1, a novel target protein of phosphorylation by pim-1 kinasePim-1 translocates sorting nexin 6/TRAF4-associated factor 2 from cytoplasm to nucleusThe PIM kinases in hematological cancersThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointConditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasiaDoes heterochromatin protein 1 always follow code?Phosphorylation site mutations in heterochromatin protein 1 (HP1) reduce or eliminate silencing activity.PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc.Changed genome heterochromatinization upon prolonged activation of the Raf/ERK signaling pathway.Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1)Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Genomic microarrays: arraying order in biological chaos?A NF-κB-dependent dual promoter-enhancer initiates the lipopolysaccharide-mediated transcriptional activation of the chicken lysozyme in macrophages.EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationSequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseasesAsymmetric chromatid segregation in cardiac progenitor cells is enhanced by Pim-1 kinase.Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammationDifferential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.Phosphorylation-Dependent Targeting of Tetrahymena HP1 to Condensed ChromatinHypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation.Why target PIM1 for cancer diagnosis and treatment?The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression: HP1 acts as a positive regulator of transcription.The PIM family of serine/threonine kinases in cancer.Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors.Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancerHeterochromatin protein 1 gamma and IκB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages.Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications.Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death.RETRACTED: Gene expression analysis in response to osmotic stimuli in the intervertebral disc with DNA microarray.Analysis of transcriptional regulation of the human miR-17-92 cluster; evidence for involvement of Pim-1.Repertoire of Protein Kinases Encoded in the Genome of Takifugu rubripes.
P2860
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P2860
Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of heterochroma ...... repression function of HP1(1)
@ast
Identification of heterochroma ...... repression function of HP1(1)
@en
Identification of heterochroma ...... repression function of HP1(1)
@nl
type
label
Identification of heterochroma ...... repression function of HP1(1)
@ast
Identification of heterochroma ...... repression function of HP1(1)
@en
Identification of heterochroma ...... repression function of HP1(1)
@nl
prefLabel
Identification of heterochroma ...... repression function of HP1(1)
@ast
Identification of heterochroma ...... repression function of HP1(1)
@en
Identification of heterochroma ...... repression function of HP1(1)
@nl
P2093
P2860
P3181
P1433
P1476
Identification of heterochroma ...... repression function of HP1(1)
@en
P2093
P2860
P3181
P356
10.1016/S0014-5793(00)01105-4
P407
P577
2000-02-04T00:00:00Z