Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
about
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting proteinGolgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domainsEndofin recruits TOM1 to endosomesCrystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexinsCharacterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β productionDivalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.ADP-ribosylation factor (ARF) interaction is not sufficient for yeast GGA protein function or localization.GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factorsAutoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.Adaptins: the final recountThe human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptideMammalian GGAs act together to sort mannose 6-phosphate receptorsBinding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptinPhosphoinositide-mediated clathrin adaptor progression at the trans-Golgi networkStructural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domainsStructural basis for recognition of acidic-cluster dileucine sequence by GGA1Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocketStructure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptorLaa1p, a conserved AP-1 accessory protein important for AP-1 localization in yeast.Yeast GGA proteins interact with GTP-bound Arf and facilitate transport through the GolgiStructural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteinsMannose 6-phosphate receptors: new twists in the taleThe sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding'Srcasm: a novel Src activating and signaling moleculeGGAs: roles of the different domains and comparison with AP-1 and clathrinThe trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.GGA1 interacts with the adaptor protein AP-1 through a WNSF sequence in its hinge region.Defects in cellular sorting and retroviral assembly induced by GGA overexpressionTrichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surfaceStructural requirements for function of yeast GGAs in vacuolar protein sorting, alpha-factor maturation, and interactions with clathrin.VHS domain -- a longshoreman of vesicle lines.Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors.Trans-Golgi network sorting.The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)Domains of the TGN: coats, tethers and G proteins.A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins.
P2860
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P2860
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@ast
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@en
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@nl
type
label
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@ast
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@en
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@nl
prefLabel
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@ast
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@en
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@nl
P2860
P356
P1476
Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains
@en
P2093
P2860
P304
P356
10.1074/JBC.275.10.7176
P407
P50
P577
2000-03-01T00:00:00Z