The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein
about
Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domainsThe trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sitesSorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargoEndofin recruits TOM1 to endosomesRecognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexesA PACS-1, GGA3 and CK2 complex regulates CI-MPR traffickingSNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptorsSortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexinsRho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta productionCharacterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cellsADP-ribosylation factor (ARF) interaction is not sufficient for yeast GGA protein function or localization.Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptinsSortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factorsAutoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.Hrs recruits clathrin to early endosomesAdaptins: the final recountThe lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilinFrom noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locusEndocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor familiesWNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathwaySCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motifFurin at the cutting edge: from protein traffic to embryogenesis and diseaseInactivation of sortilin (a novel lysosomal sorting receptor) by dominant negative competition and RNA interferenceAnalysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during developmentSpadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages.Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domainsStructural basis for recognition of acidic-cluster dileucine sequence by GGA1Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocketStructure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptorIdentification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complexNovel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiaeA Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing ImpairmentStructural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteinsThe sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding
P2860
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P2860
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein
description
2001 nî lūn-bûn
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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
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2001年學術文章
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name
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@ast
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en-gb
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@nl
type
label
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@ast
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en-gb
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@nl
prefLabel
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@ast
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en-gb
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The sortilin cytoplasmic tail ...... in of the GGA2 sorting protein
@en
P2093
C M Petersen
E I Christensen
J Gliemann
R Pohlmann
P2860
P304
P3181
P356
10.1093/EMBOJ/20.9.2180
P407
P577
2001-05-01T00:00:00Z