pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer
about
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expressionSIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesIntratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancerpRb2/p130: a new candidate for retinoblastoma tumor formationThe retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycleRegulation of neuron survival and death by p130 and associated chromatin modifiers.Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence.Purification and identification of proteins that bind to the hereditary persistence of fetal hemoglobin -198 mutation in the gamma-globin gene promoterZ-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERaSynergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cellsBioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modificationsSuv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression.The many faces of estrogen signaling.Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.Sex, epilepsy, and epigenetics.The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene.Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development.Transcription and epigenetic profile of the promoter, first exon and first intron of the human tyrosine hydroxylase geneA Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells.Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice.Mechanisms of resistance to endocrine therapy in breast cancer: focus on signaling pathways, miRNAs and genetically based resistance.Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer.Identification of common tumor signatures based on gene set enrichment analysis.Epigenetic targeting in breast cancer: therapeutic impact and future direction.Epigenetic regulation of estrogen signaling in breast cancerDnmt1 deficiency promotes CAG repeat expansion in the mouse germlineGenetic and epigenetic alterations in breast cancer: what are the perspectives for clinical practice?Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcomeThe role of histone deacetylases (HDACs) in human cancer.The silent estrogen receptor--can we make it speak?Oestrogen receptor negativity in breast cancer: a cause or consequence?The switch from pRb/p105 to Rb2/p130 in DNA damage and cellular senescence.Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance.On the role of retinoblastoma family proteins in the establishment and maintenance of the epigenetic landscape.Transforming growth factor β suppresses peroxisome proliferator-activated receptor γ expression via both SMAD binding and novel TGF-β inhibitory elements.DNA methylation in hematopoietic development and disease.Inorganic arsenic exposure induces E2F-dependent G0/G1 arrest via an increase in retinoblastoma family protein p130 in B-cell lymphoma A20 cells.Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation.Analysis of HP1α regulation in human breast cancer cells.
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pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@ast
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@en
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@nl
type
label
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@ast
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@en
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@nl
prefLabel
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@ast
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@en
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@nl
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P2860
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P1476
pRb2/p130-E2F4/5-HDAC1-SUV39H1 ...... eceptor-alpha in breast cancer
@en
P2093
Antonio Russo
Giuseppe Russo
Marcella Macaluso
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P2888
P304
P3181
P356
10.1038/SJ.ONC.1206578
P407
P577
2003-06-05T00:00:00Z
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P6179
1001804345