Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
about
A newly identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitinationNp9 protein of human endogenous retrovirus K interacts with ligand of numb protein XInhibitory effects of local anesthetics on the proteasome and their biological actions.Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase.Lysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A.p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesisThe MDM2-p53 pathway revisitedInhibition of protein synthesis alters protein degradation through activation of protein kinase B (AKT)A role for Numb in p53 stabilization.Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikisMDM2's social network.Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries.Cooperation among Numb, MDM2 and p53 in the development and progression of pancreatic cancer.MDM2 protein-mediated ubiquitination of numb protein: identification of a second physiological substrate of MDM2 that employs a dual-site docking mechanismIntegrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.The Many Faces of MDM2 Binding Partners.MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis.Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway.Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.Plk1 phosphorylation of Numb leads to impaired DNA damage response.
P2860
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P2860
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@ast
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@en
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@nl
type
label
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@ast
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@en
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@nl
prefLabel
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@ast
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@en
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@nl
P2093
P1476
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase
@en
P2093
Hideyo Yasuda
Hirofumi Tanaka
Reiko Honda
Satomi Yogosawa
Yasuhiro Miyauchi
P304
P356
10.1016/S0006-291X(03)00282-1
P407
P577
2003-03-21T00:00:00Z