Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

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NRF2 Addiction in Cancer Cells.Activation of p62/SQSTM1-Keap1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Cancer.Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation ZZ-dependent regulation of p62/SQSTM1 in autophagy

P2860

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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

Item

http://www.wikidata.org/entity/Q46092740

description

2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@en

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@nl

type

Item

label

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@en

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@nl

prefLabel

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@en

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@nl

P1476

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

@en

P2093

Atsushi Umemura

http://www.w3.org/2001/XMLSchema#string

Cecille D Browne

http://www.w3.org/2001/XMLSchema#string

David Tarin

http://www.w3.org/2001/XMLSchema#string

Debanjan Dhar

http://www.w3.org/2001/XMLSchema#string

Giuseppe Di Caro

http://www.w3.org/2001/XMLSchema#string

Hannes Kessler

http://www.w3.org/2001/XMLSchema#string

Jelena Todoric

http://www.w3.org/2001/XMLSchema#string

Johan B Fagman

http://www.w3.org/2001/XMLSchema#string

Jorge Moscat

http://www.w3.org/2001/XMLSchema#string

Laura Antonucci

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway

Notch signaling controls multiple steps of pancreatic differentiation

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Mammalian Numb is a target protein of Mdm2, ubiquitin ligase

P304

824-839.e8

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P31

scholarly article

P356

10.1016/J.CCELL.2017.10.011

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Michael Karin

Michael Goggins

Tannishtha Reya

P577

2017-11-07T00:00:00Z

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P698

29153842

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P921

Aizkuņģa dziedzeris

P932

5730340

http://www.w3.org/2001/XMLSchema#string

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

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P2860

P2860

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932