Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription
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Inhibition of p53 DNA binding by human papillomavirus E6 proteinsTwo domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repressionTranscriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexesRegulation of p53 function and stability by phosphorylationHuman papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityViruses associated with human cancerAccumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21mdm2 expression is induced by wild type p53 activityVy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cellsHuman papillomavirus in esophageal squamous cell carcinoma in Colombia and Chile.Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells.Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexesHuman papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cellsHuman papillomavirus type 16 E7 maintains elevated levels of the cdc25A tyrosine phosphatase during deregulation of cell cycle arrest.Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas.Adeno-associated virus type 2 increases proteosome-dependent degradation of p21WAF1 in a human papillomavirus type 31b-positive cervical carcinoma linePitx2a binds to human papillomavirus type 18 E6 protein and inhibits E6-mediated P53 degradation in HeLa cells.Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.HPV16 early gene E5 specifically reduces miRNA-196a in cervical cancer cells.Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 proteinTranscriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor geneExpression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesionsNeuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFsGain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness.Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutantSerum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16.Natural variants of the human papillomavirus type 16 E6 protein differ in their abilities to alter keratinocyte differentiation and to induce p53 degradation.CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progressionMolecular screening of compounds to the predicted Protein-Protein Interaction site of Rb1-E7 with p53- E6 in HPV.Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damageGroup-specific differentiation between high- and low-risk human papillomavirus genotypes by general primer-mediated PCR and two cocktails of oligonucleotide probes.Altered binding site selection of p53 transcription cassettes by hepatitis B virus X proteinp53 alterations in recurrent squamous cell cancer of the head and neck refractory to radiotherapyRepression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53
P2860
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P2860
Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Human papillomavirus E6 protei ...... ed repression of transcription
@ast
Human papillomavirus E6 protei ...... ed repression of transcription
@en
Human papillomavirus E6 protei ...... ed repression of transcription
@nl
type
label
Human papillomavirus E6 protei ...... ed repression of transcription
@ast
Human papillomavirus E6 protei ...... ed repression of transcription
@en
Human papillomavirus E6 protei ...... ed repression of transcription
@nl
prefLabel
Human papillomavirus E6 protei ...... ed repression of transcription
@ast
Human papillomavirus E6 protei ...... ed repression of transcription
@en
Human papillomavirus E6 protei ...... ed repression of transcription
@nl
P2093
P2860
P1433
P1476
Human papillomavirus E6 protei ...... ed repression of transcription
@en
P2093
A B Finicle
K H Vousden
L A Laimins
M S Lechner
P2860
P304
P407
P577
1992-08-01T00:00:00Z