Solution-phase parallel synthesis of Hsp90 inhibitorsA knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databasesA chemical approach to generate molecular diversity based on the scaffold of cyclic decapeptide antibiotic tyrocidine ATrifluoroacetic anhydride-mediated solid-phase version of the Robinson-Gabriel synthesis of oxazolesCombinatorial solid-phase synthesis of hapalosin mimeticsSolid-phase organic synthesis: a critical understanding of the resin.Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library.A novel approach to high-throughput quality control of parallel synthesis libraries.Rapid access to N-substituted diketopiperazines by one-pot Ugi-4CR/deprotection+activation/cyclization (UDAC).Survey of the diversity space coverage of reported combinatorial libraries.Ultrasound-promoted copper-catalyzed azide-alkyne cycloadditionPreparative LC-MS purification: improved compound-specific method optimization.One-step synthesis of oxazoline and dihydrooxazine libraries.Fully automated open access platform for rapid, combined serial evaporation and sample reformatting.Preparation of trifluoromethylpyridine libraries.New regioselective multicomponent reaction: one pot synthesis of spiro heterobicyclic aliphatic rings.A method for the rapid synthesis of benzopyrone libraries employing a resin capture strategy.Solid phase combinatorial synthesis of a library of macro-heterocycles and related acyclic compounds.Solution phase synthesis of libraries of polycyclic natural product analogues by cascade radical annulation: synthesis of a 64-member library of mappicine analogues and a 48-member library of mappicine ketone analogues.Identification of a potent peptide deformylase inhibitor from a rationally designed combinatorial library.Ruminations regarding the design of small mixtures for biological testing.Polymer-supported tetrafluorophenol: a new activated resin for chemical library synthesis.Parallel solid-phase synthesis and structural characterization of a library of highly substituted chiral 1,3-oxazolidines.Solid phase combinatorial library of phosphinic peptides for discovery of matrix metalloproteinase inhibitors.Retrospective analysis of an experimental high-throughput screening data set by recursive partitioning.Selection of an optimized adsorbent for preparative chromatographic enantioseparation by microscale screening of a second-generation chiral stationary phase library.Evaluation of evaporative light-scattering detector for combinatorial library quantitation by reversed phase HPLC.Solid-phase synthesis of urea and amide libraries using the T2 triazene linker.A drop-on-demand ink-jet printer for combinatorial libraries and functionally graded ceramics.Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders.Rapid parallel synthesis of combinatorial libraries of substituted 3-thio-1,2,4-triazoles and 2-thioimidazoles.(19)F-encoded combinatorial libraries: discovery of selective metal binding and catalytic peptoids.Solid-phase synthesis of imidazo[4,5-b]pyridin-2-ones and related urea derivatives by cyclative cleavage of a carbamate linkage.Rapid microwave-assisted liquid-phase combinatorial synthesis of 2-(arylamino)benzimidazoles.A "double random" strategy for the preparation of saponin libraries.Linked parallel synthesis and MTT bioassay screening of substituted chalcones.Characterization of small combinatorial chemistry libraries by (1)H NMR. Quantitation with a convenient and novel internal standard.Combinatorial library of peptide isosters based on Diels-Alder reactions: identification of novel inhibitors against a recombinant cysteine protease from Leishmania mexicana.2,6-Diketopiperazines from amino acids, from solution-phase to solid-phase organic synthesis.Solution-phase synthesis of an aminomethyl-substituted biaryl library via sequential amine N-alkylation and Suzuki cross-coupling.
P1433
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P1433
description
begutachtete wissenschaftliche Fachzeitschrift
@de
peer-reviewed scientific journal
@en
revista científica
@es
rivista scientifica
@it
vědecký časopis
@cs
wetenschappelijk tijdschrift van American Chemical Society
@nl
рецензований науковий журнал
@uk
वैज्ञानिक पत्रिका
@hi
英语期刊
@zh
name
ACS Combinatorial Science
@ast
ACS Combinatorial Science
@de
ACS Combinatorial Science
@en
ACS Combinatorial Science
@es
ACS Combinatorial Science
@fr
ACS Combinatorial Science
@pl
Journal of Combinatorial Chemistry
@it
Journal of Combinatorial Chemistry
@nl
type
label
ACS Combinatorial Science
@ast
ACS Combinatorial Science
@de
ACS Combinatorial Science
@en
ACS Combinatorial Science
@es
ACS Combinatorial Science
@fr
ACS Combinatorial Science
@pl
Journal of Combinatorial Chemistry
@it
Journal of Combinatorial Chemistry
@nl
altLabel
ACS Comb. Sci.
@fr
J. Comb. Chem.
@fr
J. Comb. Chem.
@it
Journal of Combinatorial Chemistry
@fr
prefLabel
ACS Combinatorial Science
@ast
ACS Combinatorial Science
@de
ACS Combinatorial Science
@en
ACS Combinatorial Science
@es
ACS Combinatorial Science
@fr
ACS Combinatorial Science
@pl
Journal of Combinatorial Chemistry
@it
Journal of Combinatorial Chemistry
@nl
P3181
P1055
P1156
P1159
P1277
P1476
ACS Combinatorial Science
@en
P236
P3181
P407
P571
1999-01-01T00:00:00Z