The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA
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Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cellsEnzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylasesMutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing lossDNMT1 interacts with the developmental transcriptional repressor HESX1The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferaseThe de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1.Interactions within the mammalian DNA methyltransferase familyAccuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferaseDysregulated transcriptional and post-translational control of DNA methyltransferases in cancerAn insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and functionDNA demethylation and invasive cancer: implications for therapeuticsThe PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding foldsPCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNADNA methyltransferases and methyl-binding proteins of mammalsMaternal cadmium, iron and zinc levels, DNA methylation and birth weightThe RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeastMolecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferasesUsp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variantsDissection of structure and function of the N-terminal domain of mouse DNMT1 using regional frame-shift mutagenesisBioinformatics and Drug Discovery.The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoniGenetic control of individual differences in gene-specific methylation in human brain.The role of epigenetic transcription repression and DNA methyltransferases in cancer.Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assayDnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity.The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites.Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases.Twists and turns of DNA methylationIdentification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survivalZinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylationProcainamide is a specific inhibitor of DNA methyltransferase 1.Zinc and cancer: implications for LIV-1 in breast cancer.Human papillomavirus type 16 E7 oncoprotein mediates CCNA1 promoter methylation.Major and essential role for the DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions.The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.Intracytoplasmic sperm injection--an assisted reproduction technique that should make us cautious about imprinting deregulation.Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus.
P2860
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P2860
The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The activity of the murine DNA ...... fter binding to methylated DNA
@ast
The activity of the murine DNA ...... fter binding to methylated DNA
@en
The activity of the murine DNA ...... fter binding to methylated DNA
@nl
type
label
The activity of the murine DNA ...... fter binding to methylated DNA
@ast
The activity of the murine DNA ...... fter binding to methylated DNA
@en
The activity of the murine DNA ...... fter binding to methylated DNA
@nl
prefLabel
The activity of the murine DNA ...... fter binding to methylated DNA
@ast
The activity of the murine DNA ...... fter binding to methylated DNA
@en
The activity of the murine DNA ...... fter binding to methylated DNA
@nl
P2093
P3181
P356
P1476
The activity of the murine DNA ...... fter binding to methylated DNA
@en
P2093
P304
P3181
P356
10.1006/JMBI.2001.4709
P407
P577
2001-06-22T00:00:00Z