Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1
about
DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsAn insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and functionStructural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) ProteinSignalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerMBD4 interacts with and recruits USP7 to heterochromatic fociThe role of UBL domains in ubiquitin-specific proteasesThe RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeastCrystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7USP7 is a SUMO deubiquitinase essential for DNA replicationBinding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functionsMethyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.Sexual and asexual oogenesis require the expression of unique and shared sets of genes in the insect Acyrthosiphon pisum.The emerging nexus of active DNA demethylation and mitochondrial oxidative metabolism in post-mitotic neuronsDown-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer propertiesDNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryosMolecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7).M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choiceLong noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development.Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2.Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity.Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis.UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinomaZebrafish Discoveries in Cancer Epigenetics.Ub-family modifications at the replication fork: Regulating PCNA-interacting components.The role of methyl-binding proteins in chromatin organization and epigenome maintenance.Regulation of protein stability of DNA methyltransferase 1 by post-translational modificationsEpigenetics in T-cell acute lymphoblastic leukemia.Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis.PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311.DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitinationA Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma.Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.
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Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1
description
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Februar 2011 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2011/02/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/02/01)
@nl
наукова стаття, опублікована в лютому 2011
@uk
مقالة علمية (نشرت في فبراير 2011)
@ar
name
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@ast
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@en
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@nl
type
label
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@ast
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@en
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@nl
prefLabel
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@ast
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@en
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@nl
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P921
P3181
P356
P1476
Usp7 and Uhrf1 control ubiquit ...... ce DNA methyltransferase Dnmt1
@en
P2093
Heinrich Leonhardt
Weihua Qin
P2860
P304
P3181
P356
10.1002/JCB.22998
P50
P577
2011-02-01T00:00:00Z