Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions
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CCN3 (NOV) is a novel angiogenic regulator of the CCN protein familyFas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivoIntegrin alphaDbeta2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding propertiesCYR61 (CCN1) is essential for placental development and vascular integrityMatricellular protein CCN1 activates a proinflammatory genetic program in murine macrophagesFunctions and mechanisms of action of CCN matricellular proteinsDifferential expression of CCN-family members in primary human bone marrow-derived mesenchymal stem cells during osteogenic, chondrogenic and adipogenic differentiation.Cell surface receptors for CCN proteinsEyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilaritiesN-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecanOverexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient miceIdentification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61)Plasminogen on the surfaces of fibrin clots prevents adhesion of leukocytes and platelets.CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammationSignal regulatory protein alpha negatively regulates beta2 integrin-mediated monocyte adhesion, transendothelial migration and phagocytosis.Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation.Tissue factor-factor VIIa signaling.Secretome from mesenchymal stem cells induces angiogenesis via Cyr61Early and late postnatal myocardial and vascular changes in a protein restriction rat model of intrauterine growth restrictionCCN1/CYR61: the very model of a modern matricellular protein.New strategy to control cell migration and metastasis regulated by CCN2/CTGF.Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells: a therapeutic benefit for arthritis.CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins.Ligand recognition specificity of leukocyte integrin αMβ2 (Mac-1, CD11b/CD18) and its functional consequences.Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance.The opioid peptide dynorphin A induces leukocyte responses via integrin Mac-1 (αMβ2, CD11b/CD18).The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healingAngiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.CCN1 Induces β-Catenin Translocation in Esophageal Squamous Cell Carcinoma through Integrin α11.Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance.Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident MicrogliaSmad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts.CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in miceMatricellular protein CCN3 mitigates abdominal aortic aneurysm.Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase.A physiological role for connective tissue growth factor in early wound healingThe role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration.The heparan sulfate proteoglycan form of epithelial CD44v3 serves as a CD11b/CD18 counter-receptor during polymorphonuclear leukocyte transepithelial migration.Degradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retina.
P2860
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P2860
Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions
description
2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of integrin alp ...... sed in atherosclerotic lesions
@ast
Identification of integrin alp ...... sed in atherosclerotic lesions
@en
Identification of integrin alp ...... sed in atherosclerotic lesions
@nl
type
label
Identification of integrin alp ...... sed in atherosclerotic lesions
@ast
Identification of integrin alp ...... sed in atherosclerotic lesions
@en
Identification of integrin alp ...... sed in atherosclerotic lesions
@nl
prefLabel
Identification of integrin alp ...... sed in atherosclerotic lesions
@ast
Identification of integrin alp ...... sed in atherosclerotic lesions
@en
Identification of integrin alp ...... sed in atherosclerotic lesions
@nl
P2093
P1433
P1476
Identification of integrin alp ...... sed in atherosclerotic lesions
@en
P2093
Eugene E Emeson
Igor Jovanovic
Joseph M Schober
Lester F Lau
Ningyu Chen
Richard D Ye
Stephen C-T Lam
Tatiana M Grzeszkiewicz
Tatiana P Ugarova
P304
P356
10.1182/BLOOD.V99.12.4457
P407
P577
2002-06-15T00:00:00Z