The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
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Deubiquitylating enzymes and diseaseThe innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κBThe E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammationThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activationAssociation of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signalingThe inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosisStabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cellsEmerging roles for the non-canonical IKKs in cancerThe tumor suppressor CYLD regulates entry into mitosisUSP13 enzyme regulates Siah2 ligase stability and activity via noncatalytic ubiquitin-binding domainsNLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysK63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1The IkappaB kinase complex: master regulator of NF-kappaB signalingCYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulinThe tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral responseThe kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1ARegulation of MITF stability by the USP13 deubiquitinaseUSP17 regulates Ras activation and cell proliferation by blocking RCE1 activityLys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activityZinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activityAgonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulationEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentTRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaBPathogen recognition and inflammatory signaling in innate immune defensesRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesThe tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factorPost-translational modifications as key regulators of TNF-induced necroptosisPoly-ubiquitination in TNFR1-mediated necroptosisHypoxia Induced NF-κBUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINMolecular basis of hypohidrotic ectodermal dysplasia: an updateRoles of miR-182 in sensory organ development and cancerWhen ubiquitin meets NF-κB: a trove for anti-cancer drug developmentUbiquitin in the immune systemRegulation of NF-κB by ubiquitination
P2860
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P2860
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@ast
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@en
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@nl
type
label
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@ast
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@en
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@nl
prefLabel
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@ast
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@en
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@nl
P2093
P3181
P356
P1433
P1476
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
@en
P2093
Alain Israël
Andrew Kovalenko
Christine Chable-Bessia
David Wallach
Gilles Courtois
Giuseppina Cantarella
P2888
P3181
P356
10.1038/NATURE01802
P407
P577
2003-08-14T00:00:00Z
P5875
P6179
1010362117