The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies - Test2 - elhamkhani - TriplyDB

The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

http://www.wikidata.org/entity/Q28202877

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Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1 Aberrant CBFA2T3B gene promoter methylation in breast tumors Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors A distinct epigenetic signature at targets of a leukemia protein.The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues Novel RNA-binding properties of the MTG chromatin regulatory proteins.Down-regulation of microRNAs 222/221 in acute myelogenous leukemia with deranged core-binding factor subunits Bioinformatic analysis of the nucleolus.Loss of MTG16a (CBFA2T3), a novel rDNA repressor, leads to increased ribogenesis and disruption of breast acinar morphogenesis RUNX1 translocations and fusion genes in malignant hemopathies.miR-17 deregulates a core RUNX1-miRNA mechanism of CBF acute myeloid leukemia.Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation.Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer.

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The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

http://www.wikidata.org/entity/Q28202877

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

The transcriptional corepresso ...... -positive myeloid malignancies

@ast

The transcriptional corepresso ...... -positive myeloid malignancies

@en

The transcriptional corepresso ...... -positive myeloid malignancies

@nl

type

label

The transcriptional corepresso ...... -positive myeloid malignancies

@ast

The transcriptional corepresso ...... -positive myeloid malignancies

@en

The transcriptional corepresso ...... -positive myeloid malignancies

@nl

prefLabel

The transcriptional corepresso ...... -positive myeloid malignancies

@ast

The transcriptional corepresso ...... -positive myeloid malignancies

@en

The transcriptional corepresso ...... -positive myeloid malignancies

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The transcriptional corepresso ...... -positive myeloid malignancies

@en

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André T Hoogeveen

http://www.w3.org/2001/XMLSchema#string

Angelia Fenaroli

http://www.w3.org/2001/XMLSchema#string

Joris Schonkeren

http://www.w3.org/2001/XMLSchema#string

Leontine van Unen

http://www.w3.org/2001/XMLSchema#string

Luisa Schiaffonati

http://www.w3.org/2001/XMLSchema#string

Stefano Rossetti

http://www.w3.org/2001/XMLSchema#string

Violeta Stoyanova

http://www.w3.org/2001/XMLSchema#string

P2860

Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins

The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

Oligomerization of ETO is obligatory for corepressor interaction

Repression of RNA polymerase I transcription by the tumor suppressor p53

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6703-12

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scholarly article

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10.1038/SJ.ONC.1205882

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43

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21

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Nicoletta Sacchi

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2002-09-26T00:00:00Z

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11147727

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1022985726

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12242670

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