Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription
about
Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fatesAtrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cellsAtaxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptorsFunctional architecture of atrophinsLive-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressorsThe promise and perils of HDAC inhibitors in neurodegenerationThe transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignanciesNuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicityA functional screening assay for the isolation of transcription factorsDrosophila brakeless interacts with atrophin and is required for tailless-mediated transcriptional repression in early embryos.Whole-exome sequencing identifies novel candidate predisposition genes for familial polycythemia vera.Characterization of a t(5;8)(q31;q21) translocation in a patient with mental retardation and congenital heart disease: implications for involvement of RUNX1T1 in human brain and heart development.AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.A screen for genes that interact with the Drosophila pair-rule segmentation gene fushi tarazuThe corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.Polyglutamine expansion alters the dynamics and molecular architecture of aggregates in dentatorubropallidoluysian atrophyMyeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.A multidimensional approach to an in-depth proteomics analysis of transcriptional regulators in neuroblastoma cellsAtrophin proteins: an overview of a new class of nuclear receptor corepressorsConsensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.LANP mediates neuritic pathology in Spinocerebellar ataxia type 1.The expanding role for chromatin and transcription in polyglutamine disease.ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO.Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat.Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions.Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA.Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration.Divalproex sodium modulates nuclear localization of ataxin-3 and prevents cellular toxicity caused by expanded ataxin-3.Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein.Time course of polyglutamine aggregate body formation and cell death: enhanced growth in nucleus and an interval for cell death.CBFA2T3-ZNF652 corepressor complex regulates transcription of the E-box gene HEB.Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy.
P2860
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P2860
Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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Atrophin-1, the dentato-rubral ...... ix and represses transcription
@ast
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en-gb
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@nl
type
label
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@ast
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en-gb
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@nl
prefLabel
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@ast
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en-gb
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@nl
P2093
P2860
P356
P1476
Atrophin-1, the dentato-rubral ...... ix and represses transcription
@en
P2093
F C Nucifora
G Schilling
P2860
P304
P356
10.1083/JCB.150.5.939
P407
P577
2000-09-04T00:00:00Z