Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex
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Biology of IL-21 and the IL-21 receptorInterleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.The biological functions of T helper 17 cell effector cytokines in inflammationThe differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammatInterleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cellsInterleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responsesDifferential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.The role of interleukin-21 in HIV infectionGene therapy studies in a canine model of X-linked severe combined immunodeficiencyInterleukin-21 enhances rituximab activity in a cynomolgus monkey model of B cell depletion and in mouse B cell lymphoma modelsCrystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21RThe Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal FoldGPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptorInterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationAdvances of the interleukin-21 signaling pathway in immunity and angiogenesis.IL-21 mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes.Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vectorIL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanismsCellular-based therapies to prevent or reduce thrombocytopenia.IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts.B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.X-linked severe combined immunodeficiency syndrome: the first Korean case with gamma c chain gene mutation and subsequent genetic counseling.Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma.Cytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.Human lymphoid development in the absence of common γ-chain receptor signaling.Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow.A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivoMolecular pathways in the induction of interleukin-27-driven regulatory type 1 cells.T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets.Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.Interleukin-21: a multifunctional regulator of immunity to infections.Graft versus host disease in the bone marrow, liver and thymus humanized mouse model.A strategy to study pathway cross-talks of cells under repetitive exposure to stimuli.Cytokines and immunodeficiency diseases.Severe papillomavirus infection progressing to metastatic squamous cell carcinoma in bone marrow-transplanted X-linked SCID dogsMigration and differentiation of CD8+ T cells.Overview of immune system development in the dog: comparison with humans.The role of cytokines and their signaling pathways in the regulation of immunity to Toxoplasma gondii.Ex vivo γ-retroviral gene therapy of dogs with X-linked severe combined immunodeficiency and the development of a thymic T cell lymphoma.
P2860
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P2860
Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@ast
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@en
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@nl
type
label
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@ast
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@en
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@nl
prefLabel
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@ast
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@en
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@nl
P2093
P3181
P356
P1476
Cutting edge: the common gamma ...... of the IL-21 receptor complex
@en
P2093
K Sugamura
S Tsuchiya
P3181
P356
10.4049/JIMMUNOL.167.1.1
P407
P577
2001-07-01T00:00:00Z