Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
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HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxisSubunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machineryCyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9)-cyclin T1 interaction in Nef-dependent mannerHIV-1 Nef promotes infection by excluding SERINC5 from virion incorporationHIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replicationNef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathwaysHIV: master of the host cell.Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency.HIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchDendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle?The simian immunodeficiency virus targets central cell cycle functions through transcriptional repression in vivoCrystal Structure of NFAT Bound to the HIV-1 LTR Tandem κB Enhancer ElementA Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 NefOne protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell deathA hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.Dedicator of Cytokinesis 2 in Cell Signaling Regulation and Disease Development.HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenonHIV-1 Nef-mediated T-cell activation and chemotaxis are decoupled using a HIV-1/SIVpbj1.9. chimeric nef variant.The emerging role of long non-coding RNAs in HIV infection.Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAsHIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferationHuman immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1.Reconstitution and molecular analysis of an active human immunodeficiency virus type 1 Nef/p21-activated kinase 2 complex.Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell linesThe SCHOOL of nature: III. From mechanistic understanding to novel therapiesCharting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.nef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys.Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screenCooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.Cellular heat shock factor 1 positively regulates human immunodeficiency virus-1 gene expression and replication by two distinct pathways.Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions.Antigen-dependent and -independent mechanisms of T and B cell hyperactivation during chronic HIV-1 infectionReciprocal regulation of the nuclear factor of activated T cells and HIV-1.
P2860
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P2860
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@ast
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@en
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@nl
type
label
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@ast
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@en
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@nl
prefLabel
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@ast
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@en
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@nl
P2093
P1433
P1476
Nef triggers a transcriptional ...... ducing HIV virulence mediators
@en
P2093
A McMichael
V Aluvihare
P304
P356
10.1016/S1074-7613(01)00158-3
P407
P577
2001-06-01T00:00:00Z