Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling - Test2 - elhamkhani - TriplyDB

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling

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The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathway.SMARCA4/BRG1 Is a Novel Prognostic Biomarker Predictive of Cisplatin-Based Chemotherapy Outcomes in Resected Non-Small Cell Lung Cancer Mi-2 beta associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities An essential switch in subunit composition of a chromatin remodeling complex during neural development Whole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cells Flavonoids from each of the six structural groups reactivate BRM, a possible cofactor for the anticancer effects of flavonoids Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene.The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.Chromatin remodelling and actin organisation.BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression A BAF-centred view of the immune system.Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk.Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition.Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.Retinoblastoma tumor suppressor: analyses of dynamic behavior in living cells reveal multiple modes of regulation.SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.Chromatin remodeling complex in Treg function.Mechanism of BRG1 silencing in primary cancers.Small molecule regulators of Rb-E2F pathway as modulators of transcription.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.Chromatin regulators with tumor suppressor properties and their alterations in human cancers.A rationale to target the SWI/SNF complex for cancer therapy.Vulnerabilities of mutant SWI/SNF complexes in cancer.Chromatin remodeler mutations in human cancers: epigenetic implications.p53 protein regulates the effects of amifostine on apoptosis, cell cycle progression, and cytoprotection.Beyond Mutations: Additional Mechanisms and Implications of SWI/SNF Complex Inactivation.Gene silencing associated with SWI/SNF complex loss during NSCLC development.BRG1 and BRM loss selectively impacts RB and P53, respectively: BRG1 and BRM have differential functions in vivo.Roles of pRB in the Regulation of Nucleosome and Chromatin Structures.Identifying targets for the restoration and reactivation of BRM.The glucocorticoid receptor and the coregulator Brm selectively modulate each other's occupancy and activity in a gene-specific manner The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.

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Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling

http://www.wikidata.org/entity/Q28207249

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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type

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Compensation of BRG-1 function ...... oma tumor suppressor signaling

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Bernard E Weissman

http://www.w3.org/2001/XMLSchema#string

Bryan L Betz

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David N Reisman

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Erik S Knudsen

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Matthew W Strobeck

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Ranjaka W Gunawardena

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Steven P Angus

http://www.w3.org/2001/XMLSchema#string

Timothy F Kowalik

http://www.w3.org/2001/XMLSchema#string

P2860

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

Diversity and specialization of mammalian SWI/SNF complexes

BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation

High-efficiency transformation of mammalian cells by plasmid DNA

Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Histone octamer transfer by a chromatin-remodeling complex.

The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

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4782-9

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scholarly article

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4560645

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10.1074/JBC.M109532200

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P433

7

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277

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Karen E Knudsen

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2002-02-15T00:00:00Z

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11635095

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11719516

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