Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition.
about
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target geneTargeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsp65 Negatively regulates transcription of the cyclin E genePTTG1 attenuates drug-induced cellular senescenceIdentification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines.Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer.Pocket protein function in melanocyte homeostasis and neoplasia.Retinoblastoma tumor suppressor: analyses of dynamic behavior in living cells reveal multiple modes of regulation.Gene modulation associated with inhibition of liver regeneration in hepatitis B virus X transgenic miceOncogene-induced senescence: an essential role for Runx.Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model.Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway.The role of histone deacetylases (HDACs) in human cancer.Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis.Nutrient-driven O-GlcNAc cycling - think globally but act locally.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancerRetinoblastoma/p107/p130 pocket proteins: protein dynamics and interactions with target gene promoters.p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes.SWI/SNF activity is required for the repression of deoxyribonucleotide triphosphate metabolic enzymes via the recruitment of mSin3B.Drosophila RB proteins repress differentiation-specific genes via two different mechanisms.BAF57 governs androgen receptor action and androgen-dependent proliferation through SWI/SNF.Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A.p53-dependent down-regulation of telomerase is mediated by p21waf1.Hierarchical requirement of SWI/SNF in retinoblastoma tumor suppressor-mediated repression of Plk1.S Phase-specific transcription of the mouse ribonucleotide reductase R2 gene requires both a proximal repressive E2F-binding site and an upstream promoter activating region.CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression.Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents.Geminin is targeted for repression by the retinoblastoma tumor suppressor pathway through intragenic E2F sites.Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.
P2860
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P2860
Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@ast
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@en
type
label
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@ast
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@en
prefLabel
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@ast
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@en
P2093
P2860
P1476
Histone deacetylation of RB-re ...... ble for cell cycle inhibition.
@en
P2093
David A Solomon
Erik S Knudsen
Hasan Siddiqui
Ranjaka W Gunawardena
P2860
P304
P356
10.1128/MCB.23.21.7719-7731.2003
P407
P577
2003-11-01T00:00:00Z