Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas - Test2 - elhamkhani - TriplyDB

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

http://www.wikidata.org/entity/Q28207345

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The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1 Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation Somatic hypermutation of the AID transgene in B and non-B cells Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions Association of single nucleotide polymorphisms in PIM-1 gene with the risk of Korean lung cancer Rho GTPases in hematopoiesis and hemopathies Alternative induction of meiotic recombination from single-base lesions of DNA deaminases MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma Targeting the Pim kinases in multiple myeloma Molecular Pathogenesis of MALT Lymphoma Biology of double-hit B-cell lymphomas Transcriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrity The genetic landscape of diffuse large B-cell lymphoma Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination Evolution of the cancer genome 7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes AID targeting is dependent on RNA polymerase II pausing.Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome Non-immunoglobulin/BCL6 gene fusion in diffuse large B-cell lymphoma: prognostic implications A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability Hypermutation in human cancer genomes: footprints and mechanisms Targeting Pim kinases for cancer treatment: opportunities and challenges The PIM kinases in hematological cancers A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions Isotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutation PIM1 kinase as a target for cancer therapy Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65 CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis AID targeting: old mysteries and new challenges DLC1: a significant GAP in the cancer genome miR-181b negatively regulates activation-induced cytidine deaminase in B cells RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development Polymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts

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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

http://www.wikidata.org/entity/Q28207345

description

2001 nî lūn-bûn

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2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2001 թվականի հուլիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@ast

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@en

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@nl

type

label

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@ast

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@en

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@nl

prefLabel

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@ast

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

@en

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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G Nanjangud

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R Dalla-Favera

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R S Chaganti

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T Goossens

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P2860

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

Genetic instabilities in human cancers

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

c-Myc target genes involved in cell growth, apoptosis, and metabolism

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci.

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma.

Binding and suppression of the Myc transcriptional activation domain by p107.

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes.

Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma.

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