Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2
about
sameAs
The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytesA complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity.IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expressionInterleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activityOpposing activities of two novel members of the IL-1 ligand family regulate skin inflammationIncreased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand.The IL-1 cytokine family and its role in inflammation and fibrosis in the lungInterleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKsCytokines in psoriasisTranscriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defenseIndications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cellsIL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cellsSystematic identification and characterization of novel human skin-associated genes encoding membrane and secreted proteinsPsoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalkImmune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.Allelic variants of IL1R1 gene associate with severe hand osteoarthritis.An autoinflammatory disease due to homozygous deletion of the IL1RN locus.IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin.IL-1 family nomenclature.IL-36α exerts pro-inflammatory effects in the lungs of miceAssessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis.The double-stranded RNA analogue polyinosinic-polycytidylic acid induces keratinocyte pyroptosis and release of IL-36γ.The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasisIL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses.Interleukin-1 and neuronal injury.The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders.The severity of experimental arthritis is independent of IL-36 receptor signaling.Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.Interleukin-1beta: a bridge between inflammation and excitotoxicity?Immunohistochemical Comparison of IL-36 and the IL-23/Th17 Axis of Generalized Pustular Psoriasis and Acute Generalized Exanthematous PustulosisInflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes.Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.The biological and clinical importance of the 'new generation' cytokines in rheumatic diseasesMutations in IL36RN are associated with geographic tongue.Targeting the IL-1 family members in skin inflammation.New Insights in the Immunobiology of IL-1 Family Members.The chicken IL-1 family: evolution in the context of the studied vertebrate lineage.IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis.Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.
P2860
Q21195661-89826635-7AEC-4C0C-BD0D-6F72272F7D4CQ24536244-FEEBEAB6-D9C6-43C2-8C81-17A707B7ED34Q24620194-55583C32-747B-444E-B1D5-27BC5E0B7BA4Q24630062-FF298CE5-E50C-40E7-A493-5E6F5A7DD064Q24676343-C7480206-EA58-4D12-9E0C-65E9D73A5945Q24794124-648139AE-33E0-40EC-8162-2FF7999B3E59Q26752849-540D4D41-A97F-4184-912E-E6F0D0C99A15Q28239808-BA652DDB-E2E9-401C-965A-F66D8ACA66FDQ28255491-FE71ECEC-6B87-4DEB-9CD9-CE12F070B7C3Q28306619-4C816948-8E23-4348-B84A-ACBBF95E8BDCQ28392117-85FE44B3-DE09-4D53-B183-C01AD4F7D724Q28513686-77473702-BCF5-4849-8CF4-37C118738243Q28534046-9AD7BC83-74FF-445E-856D-16CEE3C027A1Q28587108-E4553E7B-92C1-42BC-B3E9-AA490794E5F0Q30985619-F467E78E-DD0C-4131-B1E6-05C97762BD6EQ33547675-D1F3F676-35DB-442C-AFBC-01A5C146ABB0Q33577198-E5441EE9-91D3-4AB2-A788-8B01A080A007Q33723794-DB7959BA-7897-4E1E-9C06-1C3843E54220Q34144622-3213115D-164F-4AEB-82B8-28ED8FA8AB07Q34430063-4683A6A4-A016-4B2D-9E93-90BA25D67045Q35083987-ACDD7E94-5CC5-465F-BBEC-BC30AC674773Q35794591-5EED59E5-6247-4A11-9E44-22CD609B8A28Q35888523-476A61C9-CCD3-46D3-B15A-912FEC80929AQ35928147-7CC27150-DEF3-4ABB-A1DD-B2477C151854Q36070562-257B2F56-DC83-4495-8B55-8363FA7C164EQ36202191-34D47560-3A9A-4308-B729-68F07A19FB94Q36859216-2305C7D2-885F-4D42-9D41-212AC9C709C9Q36903300-01CCF352-C44F-4671-B253-DC8F09728676Q36994761-2AEA7B40-1916-411C-BA47-ACA1E3BA34CAQ37100241-7083DAF8-E816-4FCC-9FDD-A144A5AE152CQ37144182-A47571CC-3484-4E7B-9073-3D53C64A876AQ37205701-8F7FE896-B2B2-42CF-B985-5595A95AEB46Q37476963-A926CC53-288F-4FD5-8B6B-F5EA6565E0D8Q37516563-1A489E1E-6F9D-4B58-B4AE-4DDECD7806A6Q37601487-DFF1400D-C429-48CD-B708-7C071014512AQ37820911-A90F1D18-30C6-4E0C-8D79-B3D5CAA16064Q38121074-B9099A20-7C4F-44DB-91CB-D81234E62E51Q38215109-0658D872-1CDA-4A9A-B823-C52C99767CE9Q38438511-E05A88E7-9A05-4B84-B180-5157054AC754Q38600649-F4964068-15F2-4229-B3E4-6C83473EED16
P2860
Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@ast
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@en
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@nl
type
label
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@ast
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@en
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@nl
prefLabel
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@ast
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@en
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@nl
P2093
P3181
P1476
Two novel IL-1 family members, ...... L-1 receptor-related protein 2
@en
P2093
J C Timans
R A Kastelein
S Zurawski
P304
P3181
P356
10.4049/JIMMUNOL.167.3.1440
P407
P577
2001-08-01T00:00:00Z