Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models. - Test2 - elhamkhani - TriplyDB

Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.

Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.

http://www.wikidata.org/entity/Q35083987

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IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings Psoriasis genetics: breaking the barrier Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders Biomarkers of An Autoimmune Skin Disease--Psoriasis Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases Cytokines in psoriasis IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis Noncanonical microRNAs and endogenous siRNAs in normal and psoriatic human skin SKINOMICS: Transcriptional Profiling in Dermatology and Skin Biology Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis.Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.Establishment and function of tissue-resident innate lymphoid cells in the skin.Interferon and biologic signatures in dermatomyositis skin: specificity and heterogeneity across diseases TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier.Heterogeneity of inflammatory and cytokine networks in chronic plaque psoriasis.Transcriptome classification reveals molecular subtypes in psoriasis Cross-study homogeneity of psoriasis gene expression in skin across a large expression range.Proteomics of skin proteins in psoriasis: from discovery and verification in a mouse model to confirmation in humans.Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN.Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice.Combined use of laser capture microdissection and cDNA microarray analysis identifies locally expressed disease-related genes in focal regions of psoriasis vulgaris skin lesions.Network analysis of psoriasis reveals biological pathways and roles for coding and long non-coding RNAs.Computational Systems Biology of Psoriasis: Are We Ready for the Age of Omics and Systems Biomarkers?Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris.A subset of methylated CpG sites differentiate psoriatic from normal skin.Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis.NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis Selective programming of CCR10(+) innate lymphoid cells in skin-draining lymph nodes for cutaneous homeostatic regulation.

P2860

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P2860

Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.

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description

2010 nî lūn-bûn

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James T Elder

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Johann E Gudjonsson

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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10.1038/JID.2010.36

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7

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