Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
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The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophilsA pharmacological map of the PI3-K family defines a role for p110alpha in insulin signalingPhosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damageInterferon-γ activates transglutaminase 2 via a phosphatidylinositol-3-kinase-dependent pathway: implications for celiac sprue therapyPhosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretionMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesTargeting p110gamma in gastrointestinal cancers: attack on multiple frontsIdelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, and Follicular LymphomaSyk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytesPI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitorsStructural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitorsSignaling by the phosphoinositide 3-kinase family in immune cellsTreponema denticola major outer sheath protein impairs the cellular phosphoinositide balance that regulates neutrophil chemotaxisStudy on improving the selectivity of compounds that inhibit two PI3Ks (gamma and delta).The role of endothelial PI3Kgamma activity in neutrophil trafficking.Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion.Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.The mechanisms of up-regulation of dendritic cell activity by oxidative stressControl of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.Small-molecule inhibitors of the PI3K signaling networkCombination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors.The signaling mechanisms underlying cell polarity and chemotaxisTargeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations.PI3K: from the bench to the clinic and back.Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils.Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survivalTransport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity.Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes.Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δThe role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gelsTargeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δA chemical biology approach identified PI3K as a potential therapeutic target for neurofibromatosis type 2Ca(2+), calpain and 3-phosphorylated phosphatidyl inositides; decision-making signals in neutrophils as potential targets for therapeutics.MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion.Moving forward: mechanisms of chemoattractant gradient sensing.
P2860
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P2860
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@ast
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@en
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@nl
type
label
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@ast
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@en
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@nl
prefLabel
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@ast
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@en
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@nl
P2093
P3181
P1476
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
@en
P2093
Boris Masinovsky
C Gregory Sowell
Chanchal Sadhu
Donald E Staunton
P304
P3181
P356
10.4049/JIMMUNOL.170.5.2647
P407
P577
2003-03-01T00:00:00Z