A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
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The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell divisionSubcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progressionDynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles.The Ran Pathway in Drosophila melanogaster MitosisActivators of G protein signaling exhibit broad functionality and define a distinct core signaling triadMolecular pathways regulating mitotic spindle orientation in animal cellsPar1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytesStructural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein Subunit MutantsLGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA PathwaysInscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisionsCrystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from GαiAsymmetric cell division of stem and progenitor cells during homeostasis and cancerIdentification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of GialphaThe PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteinsEukaryotic cells and their cell bodies: Cell Theory revisedAsymmetric cell divisions promote stratification and differentiation of mammalian skin.NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic SpindleCell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.The PAR proteins: fundamental players in animal cell polarization.LGN regulates mitotic spindle orientation during epithelial morphogenesis.Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans.Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation.Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domainRic-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle.ABL1 regulates spindle orientation in adherent cells and mammalian skin.Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachmentError-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension.Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsNuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions.The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle OrientationA high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.An Arabidopsis protein with a novel calcium-binding repeat sequence interacts with TONSOKU/MGOUN3/BRUSHY1 involved in meristem maintenance.NuMA is required for proper spindle assembly and chromosome alignment in prometaphase.BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells.Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation.
P2860
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P2860
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@ast
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@en
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@nl
type
label
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@ast
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@en
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@nl
prefLabel
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@ast
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@en
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@nl
P2860
P356
P1433
P1476
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
@en
P2093
I G Macara
P2860
P2888
P304
P356
10.1038/NCB1201-1069
P407
P577
2001-12-01T00:00:00Z
P6179
1048885429